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Page 1
Interrogation of enhancer function by enhancer-targeting CRISPR epigenetic editing.
Nat Commun. 2020 Jan 24;11(1):485. doi: 10.1038/s41467-020-14362-5.
Nat Commun. 2020.
PMID: 31980609
Free PMC article.
Metabolon formation regulates branched-chain amino acid oxidation and homeostasis.
Patrick M, Gu Z, Zhang G, Wynn RM, Kaphle P, Cao H, Vu H, Cai F, Gao X, Zhang Y, Chen M, Ni M, Chuang DT, DeBerardinis RJ, Xu J.
Patrick M, et al. Among authors: kaphle p.
Nat Metab. 2022 Dec;4(12):1775-1791. doi: 10.1038/s42255-022-00689-4. Epub 2022 Nov 28.
Nat Metab. 2022.
PMID: 36443523
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Disabling Uncompetitive Inhibition of Oncogenic IDH Mutations Drives Acquired Resistance.
Lyu J, Liu Y, Gong L, Chen M, Madanat YF, Zhang Y, Cai F, Gu Z, Cao H, Kaphle P, Kim YJ, Kalkan FN, Stephens H, Dickerson KE, Ni M, Chen W, Patel P, Mims AS, Borate U, Burd A, Cai SF, Yin CC, You MJ, Chung SS, Collins RH, DeBerardinis RJ, Liu X, Xu J.
Lyu J, et al. Among authors: kaphle p.
Cancer Discov. 2023 Jan 9;13(1):170-193. doi: 10.1158/2159-8290.CD-21-1661.
Cancer Discov. 2023.
PMID: 36222845
Free PMC article.
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Structural variation cooperates with permissive chromatin to control enhancer hijacking-mediated oncogenic transcription.
Botten GA, Zhang Y, Dudnyk K, Kim YJ, Liu X, Sanders JT, Imanci A, Droin N, Cao H, Kaphle P, Dickerson KE, Kumar KR, Chen M, Chen W, Solary E, Ly P, Zhou J, Xu J.
Botten GA, et al. Among authors: kaphle p.
Blood. 2023 Jul 27;142(4):336-351. doi: 10.1182/blood.2022017555.
Blood. 2023.
PMID: 36947815
Free PMC article.
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Convergence of oncogenic cooperation at single-cell and single-gene levels drives leukemic transformation.
Liu Y, Gu Z, Cao H, Kaphle P, Lyu J, Zhang Y, Hu W, Chung SS, Dickerson KE, Xu J.
Liu Y, et al. Among authors: kaphle p.
Nat Commun. 2021 Nov 3;12(1):6323. doi: 10.1038/s41467-021-26582-4.
Nat Commun. 2021.
PMID: 34732703
Free PMC article.
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The mechanical and pharmacological regulation of glioblastoma cell migration in 3D matrices.
Kaphle P, Li Y, Yao L.
Kaphle P, et al.
J Cell Physiol. 2019 Apr;234(4):3948-3960. doi: 10.1002/jcp.27209. Epub 2018 Aug 21.
J Cell Physiol. 2019.
PMID: 30132879
Free PMC article.
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