Pratt WB - Search Results

1

Characterization of the protein-protein interactions determining the heat shock protein (hsp90.hsp70.hsp56) heterocomplex.

Czar MJ, Owens-Grillo JK, Dittmar KD, Hutchison KA, Zacharek AM, Leach KL, Deibel MR Jr, Pratt WB. Czar MJ, et al. Among authors: pratt wb. J Biol Chem. 1994 Apr 15;269(15):11155-61. J Biol Chem. 1994. PMID: 8157642 Free article.

2

Selective molybdate-directed covalent modification of sulfhydryl groups in the steroid-binding versus the DNA-binding domain of the glucocorticoid receptor.

Meshinchi S, Matić G, Hutchison KA, Pratt WB. Meshinchi S, et al. Among authors: pratt wb. J Biol Chem. 1990 Jul 15;265(20):11643-9. J Biol Chem. 1990. PMID: 2365690 Free article.

3

The native v-Raf.hsp90.p50 heterocomplex contains a novel immunophilin of the FK506 binding class.

Stancato LF, Chow YH, Owens-Grillo JK, Yem AW, Deibel MR Jr, Jove R, Pratt WB. Stancato LF, et al. Among authors: pratt wb. J Biol Chem. 1994 Sep 2;269(35):22157-61. J Biol Chem. 1994. PMID: 7520912 Free article.

4

The 23-kDa acidic protein in reticulocyte lysate is the weakly bound component of the hsp foldosome that is required for assembly of the glucocorticoid receptor into a functional heterocomplex with hsp90.

Hutchison KA, Stancato LF, Owens-Grillo JK, Johnson JL, Krishna P, Toft DO, Pratt WB. Hutchison KA, et al. Among authors: pratt wb. J Biol Chem. 1995 Aug 11;270(32):18841-7. doi: 10.1074/jbc.270.32.18841. J Biol Chem. 1995. PMID: 7642537 Free article.

5

The cyclosporin A-binding immunophilin CyP-40 and the FK506-binding immunophilin hsp56 bind to a common site on hsp90 and exist in independent cytosolic heterocomplexes with the untransformed glucocorticoid receptor.

Owens-Grillo JK, Hoffmann K, Hutchison KA, Yem AW, Deibel MR Jr, Handschumacher RE, Pratt WB. Owens-Grillo JK, et al. Among authors: pratt wb. J Biol Chem. 1995 Sep 1;270(35):20479-84. doi: 10.1074/jbc.270.35.20479. J Biol Chem. 1995. PMID: 7657624 Free article.

6

FK506 binding to the 56-kilodalton immunophilin (Hsp56) in the glucocorticoid receptor heterocomplex has no effect on receptor folding or function.

Hutchison KA, Scherrer LC, Czar MJ, Ning Y, Sanchez ER, Leach KL, Deibel MR Jr, Pratt WB. Hutchison KA, et al. Among authors: pratt wb. Biochemistry. 1993 Apr 20;32(15):3953-7. doi: 10.1021/bi00066a015. Biochemistry. 1993. PMID: 7682438

7

The hsp56 immunophilin component of untransformed steroid receptor complexes is localized both to microtubules in the cytoplasm and to the same nonrandom regions within the nucleus as the steroid receptor.

Czar MJ, Owens-Grillo JK, Yem AW, Leach KL, Deibel MR Jr, Welsh MJ, Pratt WB. Czar MJ, et al. Among authors: pratt wb. Mol Endocrinol. 1994 Dec;8(12):1731-41. doi: 10.1210/mend.8.12.7708060. Mol Endocrinol. 1994. PMID: 7708060

8

All of the factors required for assembly of the glucocorticoid receptor into a functional heterocomplex with heat shock protein 90 are preassociated in a self-sufficient protein folding structure, a "foldosome".

Hutchison KA, Dittmar KD, Pratt WB. Hutchison KA, et al. Among authors: pratt wb. J Biol Chem. 1994 Nov 11;269(45):27894-9. J Biol Chem. 1994. PMID: 7961721 Free article.

9

Proof that hsp70 is required for assembly of the glucocorticoid receptor into a heterocomplex with hsp90.

Hutchison KA, Dittmar KD, Czar MJ, Pratt WB. Hutchison KA, et al. Among authors: pratt wb. J Biol Chem. 1994 Feb 18;269(7):5043-9. J Biol Chem. 1994. PMID: 8106480 Free article.

10

Regulation of glucocorticoid receptor function through assembly of a receptor-heat shock protein complex.

Hutchison KA, Scherrer LC, Czar MJ, Stancato LF, Chow YH, Jove R, Pratt WB. Hutchison KA, et al. Among authors: pratt wb. Ann N Y Acad Sci. 1993 Jun 11;684:35-48. doi: 10.1111/j.1749-6632.1993.tb32269.x. Ann N Y Acad Sci. 1993. PMID: 8317846 Free article. Review.

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