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A molecular network of conserved factors keeps ribosomes dormant in the egg.
Leesch F, Lorenzo-Orts L, Pribitzer C, Grishkovskaya I, Roehsner J, Chugunova A, Matzinger M, Roitinger E, Belačić K, Kandolf S, Lin TY, Mechtler K, Meinhart A, Haselbach D, Pauli A. Leesch F, et al. Among authors: pribitzer c. Nature. 2023 Jan;613(7945):712-720. doi: 10.1038/s41586-022-05623-y. Epub 2023 Jan 18. Nature. 2023. PMID: 36653451 Free PMC article.
ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers.
Yelagandula R, Stecher K, Novatchkova M, Michetti L, Michlits G, Wang J, Hofbauer P, Vainorius G, Pribitzer C, Isbel L, Mendjan S, Schübeler D, Elling U, Brennecke J, Bell O. Yelagandula R, et al. Among authors: pribitzer c. Nat Cell Biol. 2023 Jan;25(1):42-55. doi: 10.1038/s41556-022-01051-2. Epub 2023 Jan 5. Nat Cell Biol. 2023. PMID: 36604593 Free PMC article.
Reprogramming CBX8-PRC1 function with a positive allosteric modulator.
Suh JL, Bsteh D, Hart B, Si Y, Weaver TM, Pribitzer C, Lau R, Soni S, Ogana H, Rectenwald JM, Norris JL, Cholensky SH, Sagum C, Umana JD, Li D, Hardy B, Bedford MT, Mumenthaler SM, Lenz HJ, Kim YM, Wang GG, Pearce KH, James LI, Kireev DB, Musselman CA, Frye SV, Bell O. Suh JL, et al. Among authors: pribitzer c. Cell Chem Biol. 2022 Apr 21;29(4):555-571.e11. doi: 10.1016/j.chembiol.2021.10.003. Epub 2021 Oct 28. Cell Chem Biol. 2022. PMID: 34715055 Free PMC article.
eIF4E1b is a non-canonical eIF4E protecting maternal dormant mRNAs.
Lorenzo-Orts L, Strobl M, Steinmetz B, Leesch F, Pribitzer C, Roehsner J, Schutzbier M, Dürnberger G, Pauli A. Lorenzo-Orts L, et al. Among authors: pribitzer c. EMBO Rep. 2024 Jan;25(1):404-427. doi: 10.1038/s44319-023-00006-4. Epub 2023 Dec 14. EMBO Rep. 2024. PMID: 38177902 Free PMC article.
Parallel PRC2/cPRC1 and vPRC1 pathways silence lineage-specific genes and maintain self-renewal in mouse embryonic stem cells.
Zepeda-Martinez JA, Pribitzer C, Wang J, Bsteh D, Golumbeanu S, Zhao Q, Burkard TR, Reichholf B, Rhie SK, Jude J, Moussa HF, Zuber J, Bell O. Zepeda-Martinez JA, et al. Among authors: pribitzer c. Sci Adv. 2020 Apr 1;6(14):eaax5692. doi: 10.1126/sciadv.aax5692. eCollection 2020 Apr. Sci Adv. 2020. PMID: 32270030 Free PMC article.
Evolutionary conservation of the eumetazoan gene regulatory landscape.
Schwaiger M, Schönauer A, Rendeiro AF, Pribitzer C, Schauer A, Gilles AF, Schinko JB, Renfer E, Fredman D, Technau U. Schwaiger M, et al. Among authors: pribitzer c. Genome Res. 2014 Apr;24(4):639-50. doi: 10.1101/gr.162529.113. Epub 2014 Mar 18. Genome Res. 2014. PMID: 24642862 Free PMC article.