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Cerebral amyloid angiopathy and Alzheimer disease - one peptide, two pathways.
Greenberg SM, Bacskai BJ, Hernandez-Guillamon M, Pruzin J, Sperling R, van Veluw SJ. Greenberg SM, et al. Among authors: pruzin j. Nat Rev Neurol. 2020 Jan;16(1):30-42. doi: 10.1038/s41582-019-0281-2. Epub 2019 Dec 11. Nat Rev Neurol. 2020. PMID: 31827267 Free PMC article. Review.
Associations of Physical Activity and β-Amyloid With Longitudinal Cognition and Neurodegeneration in Clinically Normal Older Adults.
Rabin JS, Klein H, Kirn DR, Schultz AP, Yang HS, Hampton O, Jiang S, Buckley RF, Viswanathan A, Hedden T, Pruzin J, Yau WW, Guzmán-Vélez E, Quiroz YT, Properzi M, Marshall GA, Rentz DM, Johnson KA, Sperling RA, Chhatwal JP. Rabin JS, et al. Among authors: pruzin j. JAMA Neurol. 2019 Oct 1;76(10):1203-1210. doi: 10.1001/jamaneurol.2019.1879. JAMA Neurol. 2019. PMID: 31312836 Free PMC article.
Amyloid-beta burden predicts prospective decline in body mass index in clinically normal adults.
Rabin JS, Shirzadi Z, Swardfager W, MacIntosh BJ, Schultz A, Yang HS, Buckley RF, Gatchel JR, Kirn D, Pruzin JJ, Hedden T, Lipsman N, Rentz DM, Black SE, Johnson KA, Sperling RA, Chhatwal JP; Harvard Aging Brain Study; Alzheimer's Disease Neuroimaging Initiative. Rabin JS, et al. Among authors: pruzin jj. Neurobiol Aging. 2020 Sep;93:124-130. doi: 10.1016/j.neurobiolaging.2020.03.002. Epub 2020 Mar 7. Neurobiol Aging. 2020. PMID: 32249013 Free PMC article.
Plasma IL-12/IFN-γ axis predicts cognitive trajectories in cognitively unimpaired older adults.
Yang HS, Zhang C, Carlyle BC, Zhen SY, Trombetta BA, Schultz AP, Pruzin JJ, Fitzpatrick CD, Yau WW, Kirn DR, Rentz DM, Arnold SE, Johnson KA, Sperling RA, Chhatwal JP, Tanzi RE. Yang HS, et al. Among authors: pruzin jj. Alzheimers Dement. 2022 Apr;18(4):645-653. doi: 10.1002/alz.12399. Epub 2021 Jun 23. Alzheimers Dement. 2022. PMID: 34160128 Free PMC article.
Physical activity is associated with increased resting-state functional connectivity in networks predictive of cognitive decline in clinically unimpaired older adults.
Pruzin JJ, Klein H, Rabin JS, Schultz AP, Kirn DR, Yang HS, Buckley RF, Scott MR, Properzi M, Rentz DM, Johnson KA, Sperling RA, Chhatwal JP. Pruzin JJ, et al. Alzheimers Dement (Amst). 2022 Jul 7;14(1):e12319. doi: 10.1002/dad2.12319. eCollection 2022. Alzheimers Dement (Amst). 2022. PMID: 35821672 Free PMC article.
Two Phase 3 Trials of Gantenerumab in Early Alzheimer's Disease.
Bateman RJ, Smith J, Donohue MC, Delmar P, Abbas R, Salloway S, Wojtowicz J, Blennow K, Bittner T, Black SE, Klein G, Boada M, Grimmer T, Tamaoka A, Perry RJ, Turner RS, Watson D, Woodward M, Thanasopoulou A, Lane C, Baudler M, Fox NC, Cummings JL, Fontoura P, Doody RS; GRADUATE I and II Investigators and the Gantenerumab Study Group. Bateman RJ, et al. N Engl J Med. 2023 Nov 16;389(20):1862-1876. doi: 10.1056/NEJMoa2304430. N Engl J Med. 2023. PMID: 37966285 Clinical Trial.
Diabetes, Hemoglobin A1C, and Regional Alzheimer Disease and Infarct Pathology.
Pruzin JJ, Schneider JA, Capuano AW, Leurgans SE, Barnes LL, Ahima RS, Arnold SE, Bennett DA, Arvanitakis Z. Pruzin JJ, et al. Alzheimer Dis Assoc Disord. 2017 Jan-Mar;31(1):41-47. doi: 10.1097/WAD.0000000000000172. Alzheimer Dis Assoc Disord. 2017. PMID: 27755004 Free PMC article.
Effect of apolipoprotein genotype and educational attainment on cognitive function in autosomal dominant Alzheimer's disease.
Langella S, Barksdale NG, Vasquez D, Aguillon D, Chen Y, Su Y, Acosta-Baena N, Acosta-Uribe J, Baena AY, Garcia-Ospina G, Giraldo-Chica M, Tirado V, Muñoz C, Ríos-Romenets S, Guzman-Martínez C, Oliveira G, Yang HS, Vila-Castelar C, Pruzin JJ, Ghisays V, Arboleda-Velasquez JF, Kosik KS, Reiman EM, Lopera F, Quiroz YT. Langella S, et al. Among authors: pruzin jj. Nat Commun. 2023 Aug 23;14(1):5120. doi: 10.1038/s41467-023-40775-z. Nat Commun. 2023. PMID: 37612284 Free PMC article.
24 results