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A Natural Plant Ingredient, Menthone, Regulates T Cell Subtypes and Lowers Pro-inflammatory Cytokines of Rheumatoid Arthritis.
Chen X, Wu Q, Gong Z, Ren T, Du Q, Yuan Y, Zuo Y, Miao Y, He J, Qiao C, Zheng Z, Zhang T, Huang L, Xie Z, Wang J, Zhu Y, Zhu C, Xu Y, Wu D, Gong F, Cheng J, Wen C, Zheng H. Chen X, et al. Among authors: qiao c. J Nat Prod. 2022 Apr 22;85(4):1109-1117. doi: 10.1021/acs.jnatprod.1c01231. Epub 2022 Mar 18. J Nat Prod. 2022. PMID: 35302365 Review.
LATS1 is a central signal transmitter for achieving full type-I interferon activity.
Zuo Y, He J, Liu S, Xu Y, Liu J, Qiao C, Zang L, Sun W, Yuan Y, Zhang H, Chen X, Jin L, Miao Y, Huang F, Ren T, Wang J, Qian F, Zhu C, Zhang W, Liu Y, Xu G, Ma F, Zheng H. Zuo Y, et al. Among authors: qiao c. Sci Adv. 2022 Apr 8;8(14):eabj3887. doi: 10.1126/sciadv.abj3887. Epub 2022 Apr 8. Sci Adv. 2022. PMID: 35394840 Free PMC article.
E3 ubiquitin ligase MID1 ubiquitinates and degrades type-I interferon receptor 2.
Chen X, Zhao Q, Xu Y, Wu Q, Zhang R, Du Q, Miao Y, Zuo Y, Zhang HG, Huang F, Ren T, He J, Qiao C, Li Y, Li S, Xu Y, Wu D, Yu Z, Lv H, Wang J, Zheng H, Yuan Y. Chen X, et al. Among authors: qiao c. Immunology. 2022 Nov;167(3):398-412. doi: 10.1111/imm.13544. Epub 2022 Jul 23. Immunology. 2022. PMID: 35794827 Free article.
Menthone inhibits type-I interferon signaling by promoting Tyk2 ubiquitination to relieve local inflammation of rheumatoid arthritis.
Chen X, Wu Q, Cao X, Yang Y, Gong Z, Ren T, Du Q, Yuan Y, Zuo Y, Miao Y, He J, Qiao C, Zheng Z, Zhang T, Xu Y, Wu D, Wang Q, Huang L, Xie Z, Lv H, Wang J, Gong F, Liu Z, Wen C, Zheng H. Chen X, et al. Among authors: qiao c. Int Immunopharmacol. 2022 Nov;112:109228. doi: 10.1016/j.intimp.2022.109228. Epub 2022 Sep 9. Int Immunopharmacol. 2022. PMID: 36095947
1,513 results