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Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma.
Shi Y, Lim SK, Liang Q, Iyer SV, Wang HY, Wang Z, Xie X, Sun D, Chen YJ, Tabar V, Gutin P, Williams N, De Brabander JK, Parada LF. Shi Y, et al. Among authors: liang q. Nature. 2019 Mar;567(7748):341-346. doi: 10.1038/s41586-019-0993-x. Epub 2019 Mar 6. Nature. 2019. PMID: 30842654 Free PMC article.
Structural basis for itraconazole-mediated NPC1 inhibition.
Long T, Qi X, Hassan A, Liang Q, De Brabander JK, Li X. Long T, et al. Among authors: liang q. Nat Commun. 2020 Jan 9;11(1):152. doi: 10.1038/s41467-019-13917-5. Nat Commun. 2020. PMID: 31919352 Free PMC article.
An adipo-biliary-uridine axis that regulates energy homeostasis.
Deng Y, Wang ZV, Gordillo R, An Y, Zhang C, Liang Q, Yoshino J, Cautivo KM, De Brabander J, Elmquist JK, Horton JD, Hill JA, Klein S, Scherer PE. Deng Y, et al. Among authors: liang q. Science. 2017 Mar 17;355(6330):eaaf5375. doi: 10.1126/science.aaf5375. Epub 2017 Mar 16. Science. 2017. PMID: 28302796 Free PMC article.
Triazoles inhibit cholesterol export from lysosomes by binding to NPC1.
Trinh MN, Lu F, Li X, Das A, Liang Q, De Brabander JK, Brown MS, Goldstein JL. Trinh MN, et al. Among authors: liang q. Proc Natl Acad Sci U S A. 2017 Jan 3;114(1):89-94. doi: 10.1073/pnas.1619571114. Epub 2016 Dec 19. Proc Natl Acad Sci U S A. 2017. PMID: 27994139 Free PMC article.
13 results