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Structural basis of omega-3 fatty acid transport across the blood-brain barrier.
Cater RJ, Chua GL, Erramilli SK, Keener JE, Choy BC, Tokarz P, Chin CF, Quek DQY, Kloss B, Pepe JG, Parisi G, Wong BH, Clarke OB, Marty MT, Kossiakoff AA, Khelashvili G, Silver DL, Mancia F. Cater RJ, et al. Among authors: quek dqy. Nature. 2021 Jul;595(7866):315-319. doi: 10.1038/s41586-021-03650-9. Epub 2021 Jun 16. Nature. 2021. PMID: 34135507 Free PMC article.
Inactivating mutations in MFSD2A, required for omega-3 fatty acid transport in brain, cause a lethal microcephaly syndrome.
Guemez-Gamboa A, Nguyen LN, Yang H, Zaki MS, Kara M, Ben-Omran T, Akizu N, Rosti RO, Rosti B, Scott E, Schroth J, Copeland B, Vaux KK, Cazenave-Gassiot A, Quek DQ, Wong BH, Tan BC, Wenk MR, Gunel M, Gabriel S, Chi NC, Silver DL, Gleeson JG. Guemez-Gamboa A, et al. Nat Genet. 2015 Jul;47(7):809-13. doi: 10.1038/ng.3311. Epub 2015 May 25. Nat Genet. 2015. PMID: 26005868 Free PMC article.
A partially inactivating mutation in the sodium-dependent lysophosphatidylcholine transporter MFSD2A causes a non-lethal microcephaly syndrome.
Alakbarzade V, Hameed A, Quek DQ, Chioza BA, Baple EL, Cazenave-Gassiot A, Nguyen LN, Wenk MR, Ahmad AQ, Sreekantan-Nair A, Weedon MN, Rich P, Patton MA, Warner TT, Silver DL, Crosby AH. Alakbarzade V, et al. Nat Genet. 2015 Jul;47(7):814-7. doi: 10.1038/ng.3313. Epub 2015 May 25. Nat Genet. 2015. PMID: 26005865
Cardiovascular disease and thinning of retinal nerve fiber layer in a multi-ethnic Asian population: the Singapore epidemiology of eye diseases study.
Majithia S, Quek DQY, Chee ML, Lim ZW, Nusinovici S, Soh ZD, Thakur S, Rim TH, Sabanayagam C, Cheng CY, Tham YC. Majithia S, et al. Among authors: quek dqy. Front Med (Lausanne). 2023 Oct 19;10:1235309. doi: 10.3389/fmed.2023.1235309. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37928469 Free PMC article.
Relationship between vision impairment and employment.
Chai YX, Gan ATL, Fenwick EK, Sui AY, Tan BKJ, Quek DQY, Qian C, Wong TY, Cheng CY, Lamoureux EL, Man REK. Chai YX, et al. Among authors: quek dqy. Br J Ophthalmol. 2023 Mar;107(3):361-366. doi: 10.1136/bjophthalmol-2021-319655. Epub 2021 Oct 16. Br J Ophthalmol. 2023. PMID: 34656985
11 results