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A gene-rich, transcriptionally active environment and the pre-deposition of repressive marks are predictive of susceptibility to KRAB/KAP1-mediated silencing.
Meylan S, Groner AC, Ambrosini G, Malani N, Quenneville S, Zangger N, Kapopoulou A, Kauzlaric A, Rougemont J, Ciuffi A, Bushman FD, Bucher P, Trono D. Meylan S, et al. Among authors: quenneville s. BMC Genomics. 2011 Jul 26;12:378. doi: 10.1186/1471-2164-12-378. BMC Genomics. 2011. PMID: 21791101 Free PMC article.
Liver-specific ablation of Krüppel-associated box-associated protein 1 in mice leads to male-predominant hepatosteatosis and development of liver adenoma.
Bojkowska K, Aloisio F, Cassano M, Kapopoulou A, Santoni de Sio F, Zangger N, Offner S, Cartoni C, Thomas C, Quenneville S, Johnsson K, Trono D. Bojkowska K, et al. Among authors: quenneville s. Hepatology. 2012 Oct;56(4):1279-90. doi: 10.1002/hep.25767. Epub 2012 Aug 27. Hepatology. 2012. PMID: 22684873 Free PMC article.
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