Involvement of Low-Density Lipoprotein Receptor in the Pathogenesis of Pulmonary Hypertension.
Umar S, Ruffenach G, Moazeni S, Vaillancourt M, Hong J, Cunningham C, Cao N, Navab S, Sarji S, Li M, Lee L, Fishbein G, Ardehali A, Navab M, Reddy ST, Eghbali M.
Umar S, et al. Among authors: ardehali a.
J Am Heart Assoc. 2020 Jan 21;9(2):e012063. doi: 10.1161/JAHA.119.012063. Epub 2020 Jan 9.
J Am Heart Assoc. 2020.
PMID: 31914876
Free PMC article.
LDL-R and CD36 expression levels were significantly downregulated in the lungs of patients with PH. ...Conclusions Human PH is associated with decreased LDL-R in lungs and increased oxidized LDL in lungs and plasma. WD-fed LDL-R knockout mice develop PH and r …
LDL-R and CD36 expression levels were significantly downregulated in the lungs of patients with PH. ...Conclusions Human PH is associ …