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Critical scaffolding regions of the tumor suppressor Axin1 are natively unfolded.
Noutsou M, Duarte AM, Anvarian Z, Didenko T, Minde DP, Kuper I, de Ridder I, Oikonomou C, Friedler A, Boelens R, Rüdiger SG, Maurice MM. Noutsou M, et al. Among authors: rudiger sg. J Mol Biol. 2011 Jan 21;405(3):773-86. doi: 10.1016/j.jmb.2010.11.013. Epub 2010 Nov 16. J Mol Biol. 2011. PMID: 21087614 Free article.
Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network.
Anvarian Z, Nojima H, van Kappel EC, Madl T, Spit M, Viertler M, Jordens I, Low TY, van Scherpenzeel RC, Kuper I, Richter K, Heck AJ, Boelens R, Vincent JP, Rüdiger SG, Maurice MM. Anvarian Z, et al. Among authors: rudiger sg. Nat Struct Mol Biol. 2016 Apr;23(4):324-32. doi: 10.1038/nsmb.3191. Epub 2016 Mar 14. Nat Struct Mol Biol. 2016. PMID: 26974125
Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled.
Tauriello DV, Jordens I, Kirchner K, Slootstra JW, Kruitwagen T, Bouwman BA, Noutsou M, Rüdiger SG, Schwamborn K, Schambony A, Maurice MM. Tauriello DV, et al. Among authors: rudiger sg. Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):E812-20. doi: 10.1073/pnas.1114802109. Epub 2012 Mar 12. Proc Natl Acad Sci U S A. 2012. PMID: 22411803 Free PMC article.
Stochastic machines as a colocalization mechanism for scaffold protein function.
Xue B, Romero PR, Noutsou M, Maurice MM, Rüdiger SG, William AM Jr, Mizianty MJ, Kurgan L, Uversky VN, Dunker AK. Xue B, et al. Among authors: rudiger sg. FEBS Lett. 2013 Jun 5;587(11):1587-91. doi: 10.1016/j.febslet.2013.04.006. Epub 2013 Apr 18. FEBS Lett. 2013. PMID: 23603389 Free PMC article.
Dancing with the Diva: Hsp90-Client Interactions.
Radli M, Rüdiger SGD. Radli M, et al. J Mol Biol. 2018 Sep 14;430(18 Pt B):3029-3040. doi: 10.1016/j.jmb.2018.05.026. Epub 2018 May 18. J Mol Biol. 2018. PMID: 29782836 Free article. Review.
72 results