Rüegg MA - Search Results

1

Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling.

Blättler SM, Cunningham JT, Verdeguer F, Chim H, Haas W, Liu H, Romanino K, Rüegg MA, Gygi SP, Shi Y, Puigserver P. Blättler SM, et al. Among authors: ruegg ma. Cell Metab. 2012 Apr 4;15(4):505-17. doi: 10.1016/j.cmet.2012.03.008. Cell Metab. 2012. PMID: 22482732 Free PMC article.

2

Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy.

Bentzinger CF, Romanino K, Cloëtta D, Lin S, Mascarenhas JB, Oliveri F, Xia J, Casanova E, Costa CF, Brink M, Zorzato F, Hall MN, Rüegg MA. Bentzinger CF, et al. Among authors: ruegg ma. Cell Metab. 2008 Nov;8(5):411-24. doi: 10.1016/j.cmet.2008.10.002. Cell Metab. 2008. PMID: 19046572 Free article.

3

Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy.

Risson V, Mazelin L, Roceri M, Sanchez H, Moncollin V, Corneloup C, Richard-Bulteau H, Vignaud A, Baas D, Defour A, Freyssenet D, Tanti JF, Le-Marchand-Brustel Y, Ferrier B, Conjard-Duplany A, Romanino K, Bauché S, Hantaï D, Mueller M, Kozma SC, Thomas G, Rüegg MA, Ferry A, Pende M, Bigard X, Koulmann N, Schaeffer L, Gangloff YG. Risson V, et al. Among authors: ruegg ma. J Cell Biol. 2009 Dec 14;187(6):859-74. doi: 10.1083/jcb.200903131. J Cell Biol. 2009. PMID: 20008564 Free PMC article.

4

Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function.

Romanino K, Mazelin L, Albert V, Conjard-Duplany A, Lin S, Bentzinger CF, Handschin C, Puigserver P, Zorzato F, Schaeffer L, Gangloff YG, Rüegg MA. Romanino K, et al. Among authors: ruegg ma. Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20808-13. doi: 10.1073/pnas.1111448109. Epub 2011 Dec 5. Proc Natl Acad Sci U S A. 2011. PMID: 22143799 Free PMC article.

5

Defective mitochondrial morphology and bioenergetic function in mice lacking the transcription factor Yin Yang 1 in skeletal muscle.

Blättler SM, Verdeguer F, Liesa M, Cunningham JT, Vogel RO, Chim H, Liu H, Romanino K, Shirihai OS, Vazquez F, Rüegg MA, Shi Y, Puigserver P. Blättler SM, et al. Among authors: ruegg ma. Mol Cell Biol. 2012 Aug;32(16):3333-46. doi: 10.1128/MCB.00337-12. Epub 2012 Jun 18. Mol Cell Biol. 2012. PMID: 22711985 Free PMC article.

6

Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy.

Bentzinger CF, Lin S, Romanino K, Castets P, Guridi M, Summermatter S, Handschin C, Tintignac LA, Hall MN, Rüegg MA. Bentzinger CF, et al. Among authors: ruegg ma. Skelet Muscle. 2013 Mar 6;3(1):6. doi: 10.1186/2044-5040-3-6. Skelet Muscle. 2013. PMID: 23497627 Free PMC article.

7

Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvation-induced autophagy and causes a severe, late-onset myopathy.

Castets P, Lin S, Rion N, Di Fulvio S, Romanino K, Guridi M, Frank S, Tintignac LA, Sinnreich M, Rüegg MA. Castets P, et al. Among authors: ruegg ma. Cell Metab. 2013 May 7;17(5):731-44. doi: 10.1016/j.cmet.2013.03.015. Epub 2013 Apr 18. Cell Metab. 2013. PMID: 23602450 Free article.

8

Raptor ablation in skeletal muscle decreases Cav1.1 expression and affects the function of the excitation-contraction coupling supramolecular complex.

Lopez RJ, Mosca B, Treves S, Maj M, Bergamelli L, Calderon JC, Bentzinger CF, Romanino K, Hall MN, Rüegg MA, Delbono O, Caputo C, Zorzato F. Lopez RJ, et al. Among authors: ruegg ma. Biochem J. 2015 Feb 15;466(1):123-35. doi: 10.1042/BJ20140935. Biochem J. 2015. PMID: 25431931 Free PMC article.

9

Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism.

Guridi M, Kupr B, Romanino K, Lin S, Falcetta D, Tintignac L, Rüegg MA. Guridi M, et al. Among authors: ruegg ma. Skelet Muscle. 2016 Mar 21;6:13. doi: 10.1186/s13395-016-0084-8. eCollection 2016. Skelet Muscle. 2016. PMID: 27004103 Free PMC article.

10

Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration.

Polak P, Cybulski N, Feige JN, Auwerx J, Rüegg MA, Hall MN. Polak P, et al. Among authors: ruegg ma. Cell Metab. 2008 Nov;8(5):399-410. doi: 10.1016/j.cmet.2008.09.003. Cell Metab. 2008. PMID: 19046571 Free article.

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