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Page 1
Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration.
Pepe-Mooney BJ, Dill MT, Alemany A, Ordovas-Montanes J, Matsushita Y, Rao A, Sen A, Miyazaki M, Anakk S, Dawson PA, Ono N, Shalek AK, van Oudenaarden A, Camargo FD. Pepe-Mooney BJ, et al. Cell Stem Cell. 2019 Jul 3;25(1):23-38.e8. doi: 10.1016/j.stem.2019.04.004. Epub 2019 May 9. Cell Stem Cell. 2019. PMID: 31080134 Free PMC article.
NUAK2 is a critical YAP target in liver cancer.
Yuan WC, Pepe-Mooney B, Galli GG, Dill MT, Huang HT, Hao M, Wang Y, Liang H, Calogero RA, Camargo FD. Yuan WC, et al. Nat Commun. 2018 Nov 16;9(1):4834. doi: 10.1038/s41467-018-07394-5. Nat Commun. 2018. PMID: 30446657 Free PMC article.
Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth.
Cox AG, Hwang KL, Brown KK, Evason K, Beltz S, Tsomides A, O'Connor K, Galli GG, Yimlamai D, Chhangawala S, Yuan M, Lien EC, Wucherpfennig J, Nissim S, Minami A, Cohen DE, Camargo FD, Asara JM, Houvras Y, Stainier DYR, Goessling W. Cox AG, et al. Nat Cell Biol. 2016 Aug;18(8):886-896. doi: 10.1038/ncb3389. Epub 2016 Jul 18. Nat Cell Biol. 2016. PMID: 27428308 Free PMC article.
Hippo pathway activity influences liver cell fate.
Yimlamai D, Christodoulou C, Galli GG, Yanger K, Pepe-Mooney B, Gurung B, Shrestha K, Cahan P, Stanger BZ, Camargo FD. Yimlamai D, et al. Cell. 2014 Jun 5;157(6):1324-1338. doi: 10.1016/j.cell.2014.03.060. Cell. 2014. PMID: 24906150 Free PMC article.
15 results