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Lung cancer patients' CD4(+) T cells are activated in vitro by MHC II cell-based vaccines despite the presence of myeloid-derived suppressor cells.
Cancer Immunol Immunother. 2008 Oct;57(10):1493-504. doi: 10.1007/s00262-008-0490-9. Epub 2008 Mar 6.
Cancer Immunol Immunother. 2008.
PMID: 18322683
Free PMC article.
The absence of invariant chain in MHC II cancer vaccines enhances the activation of tumor-reactive type 1 CD4+ T lymphocytes.
Thompson JA, Srivastava MK, Bosch JJ, Clements VK, Ksander BR, Ostrand-Rosenberg S.
Thompson JA, et al.
Cancer Immunol Immunother. 2008 Mar;57(3):389-98. doi: 10.1007/s00262-007-0381-5. Epub 2007 Aug 28.
Cancer Immunol Immunother. 2008.
PMID: 17724589
Free PMC article.
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