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Dual inhibitors of LSD1 and spermine oxidase.
Holshouser S, Dunworth M, Murray-Stewart T, Peterson YK, Burger P, Kirkpatrick J, Chen HH, Casero RA Jr, Woster PM. Holshouser S, et al. Medchemcomm. 2019 Feb 8;10(5):778-790. doi: 10.1039/c8md00610e. eCollection 2019 May 1. Medchemcomm. 2019. PMID: 31191868 Free PMC article.
Antibacterial Diamines Targeting Bacterial Membranes.
Wang B, Pachaiyappan B, Gruber JD, Schmidt MG, Zhang YM, Woster PM. Wang B, et al. J Med Chem. 2016 Apr 14;59(7):3140-51. doi: 10.1021/acs.jmedchem.5b01912. Epub 2016 Mar 28. J Med Chem. 2016. PMID: 26964758 Free PMC article.
Interrogating alkyl and arylalkylpolyamino (bis)urea and (bis)thiourea isosteres as potent antimalarial chemotypes against multiple lifecycle forms of Plasmodium falciparum parasites.
Verlinden BK, de Beer M, Pachaiyappan B, Besaans E, Andayi WA, Reader J, Niemand J, van Biljon R, Guy K, Egan T, Woster PM, Birkholtz LM. Verlinden BK, et al. Bioorg Med Chem. 2015 Aug 15;23(16):5131-43. doi: 10.1016/j.bmc.2015.01.036. Epub 2015 Jan 28. Bioorg Med Chem. 2015. PMID: 25684422 Free PMC article.
31 results