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The co-chaperone UNC45A is essential for the expression of mitotic kinase NEK7 and tumorigenesis.
Eisa NH, Jilani Y, Kainth K, Redd P, Lu S, Bougrine O, Abdul Sater H, Patwardhan CA, Shull A, Shi H, Liu K, Elsherbiny NM, Eissa LA, El-Shishtawy MM, Horuzsko A, Bollag R, Maihle N, Roig J, Korkaya H, Cowell JK, Chadli A. Eisa NH, et al. J Biol Chem. 2019 Apr 5;294(14):5246-5260. doi: 10.1074/jbc.RA118.006597. Epub 2019 Feb 8. J Biol Chem. 2019. PMID: 30737284 Free PMC article.
The innate immune receptor TREM-1 promotes liver injury and fibrosis.
Nguyen-Lefebvre AT, Ajith A, Portik-Dobos V, Horuzsko DD, Arbab AS, Dzutsev A, Sadek R, Trinchieri G, Horuzsko A. Nguyen-Lefebvre AT, et al. J Clin Invest. 2018 Nov 1;128(11):4870-4883. doi: 10.1172/JCI98156. Epub 2018 Oct 2. J Clin Invest. 2018. PMID: 30137027 Free PMC article.
Kupffer Cell Metabolism and Function.
Nguyen-Lefebvre AT, Horuzsko A. Nguyen-Lefebvre AT, et al. J Enzymol Metab. 2015;1(1):101. Epub 2015 Aug 14. J Enzymol Metab. 2015. PMID: 26937490 Free PMC article.