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Identification of 5-HT2A receptor signaling pathways associated with psychedelic potential.
Wallach J, Cao AB, Calkins MM, Heim AJ, Lanham JK, Bonniwell EM, Hennessey JJ, Bock HA, Anderson EI, Sherwood AM, Morris H, de Klein R, Klein AK, Cuccurazzu B, Gamrat J, Fannana T, Zauhar R, Halberstadt AL, McCorvy JD. Wallach J, et al. Nat Commun. 2023 Dec 15;14(1):8221. doi: 10.1038/s41467-023-44016-1. Nat Commun. 2023. PMID: 38102107 Free PMC article.
Identification of 5-HT2A Receptor Signaling Pathways Responsible for Psychedelic Potential.
Wallach J, Cao AB, Calkins MM, Heim AJ, Lanham JK, Bonniwell EM, Hennessey JJ, Bock HA, Anderson EI, Sherwood AM, Morris H, de Klein R, Klein AK, Cuccurazzu B, Gamrat J, Fannana T, Zauhar R, Halberstadt AL, McCorvy JD. Wallach J, et al. bioRxiv [Preprint]. 2023 Jul 31:2023.07.29.551106. doi: 10.1101/2023.07.29.551106. bioRxiv. 2023. PMID: 37577474 Free PMC article. Updated. Preprint.
(2-Aminopropyl)benzo[β]thiophenes (APBTs) are novel monoamine transporter ligands that lack stimulant effects but display psychedelic-like activity in mice.
Rudin D, McCorvy JD, Glatfelter GC, Luethi D, Szöllősi D, Ljubišić T, Kavanagh PV, Dowling G, Holy M, Jaentsch K, Walther D, Brandt SD, Stockner T, Baumann MH, Halberstadt AL, Sitte HH. Rudin D, et al. Neuropsychopharmacology. 2022 Mar;47(4):914-923. doi: 10.1038/s41386-021-01221-0. Epub 2021 Nov 8. Neuropsychopharmacology. 2022. PMID: 34750565 Free PMC article.
Investigation of the Structure-Activity Relationships of Psilocybin Analogues.
Klein AK, Chatha M, Laskowski LJ, Anderson EI, Brandt SD, Chapman SJ, McCorvy JD, Halberstadt AL. Klein AK, et al. ACS Pharmacol Transl Sci. 2020 Dec 14;4(2):533-542. doi: 10.1021/acsptsci.0c00176. eCollection 2021 Apr 9. ACS Pharmacol Transl Sci. 2020. PMID: 33860183 Free PMC article.
30 results