R01 DK113039/DK/NIDDK NIH HHS/United States[Grants and Funding] - Search Results

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Subject: R01 DK113039/DK/NIDDK NIH HHS/United States[Grant - PubMed

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Year	Number of Results
2018	1
2019	6
2020	4
2021	2
2023	3
2024	1

13 results

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Pseudohypoparathyroidism: complex disease variants with unfortunate names.

Jüppner H. Jüppner H. J Mol Endocrinol. 2023 Dec 12;72(1):e230104. doi: 10.1530/JME-23-0104. Print 2024 Jan 1. J Mol Endocrinol. 2023. PMID: 37965945 Free PMC article. Review.

Substantially Delayed Maturation of Growth Plate Chondrocytes in "Humanized" PTH1R Mice with the H223R Mutation of Jansen's Disease.

Reyes M, Firat D, Hanna P, Khan M, Bruce M, Shvedova M, Kobayashi T, Schipani E, Gardella TJ, Jüppner H. Reyes M, et al. JBMR Plus. 2023 Aug 15;7(10):e10802. doi: 10.1002/jbm4.10802. eCollection 2023 Oct. JBMR Plus. 2023. PMID: 37808400 Free PMC article.

Altered Signaling and Desensitization Responses in PTH1R Mutants Associated with Eiken Syndrome.

Portales-Castillo I, Dean T, Cheloha RW, Creemer BA, Vilardaga JP, Savransky S, Khatri A, Jüppner H, Gardella TJ. Portales-Castillo I, et al. Commun Biol. 2023 Jun 2;6(1):599. doi: 10.1038/s42003-023-04966-0. Commun Biol. 2023. PMID: 37268817 Free PMC article.

Ligand-Dependent Effects of Methionine-8 Oxidation in Parathyroid Hormone Peptide Analogues.

Daley EJ, Khatri A, Dean T, Vilardaga JP, Zaidi SA, Katritch V, Gardella TJ. Daley EJ, et al. Endocrinology. 2021 Feb 1;162(2):bqaa216. doi: 10.1210/endocr/bqaa216. Endocrinology. 2021. PMID: 33242090 Free PMC article.

A Novel GNAS Duplication Associated With Loss-of-Methylation Restricted to Exon A/B Causes Pseudohypoparathyroidism Type Ib (PHP1B).

Reyes M, Kagami M, Kawashima S, Pallotta J, Schnabel D, Fukami M, Jüppner H. Reyes M, et al. J Bone Miner Res. 2021 Mar;36(3):546-552. doi: 10.1002/jbmr.4209. Epub 2020 Nov 28. J Bone Miner Res. 2021. PMID: 33180333 Free PMC article.

Allosteric interactions in the parathyroid hormone GPCR-arrestin complex formation.

Clark LJ, Krieger J, White AD, Bondarenko V, Lei S, Fang F, Lee JY, Doruker P, Böttke T, Jean-Alphonse F, Tang P, Gardella TJ, Xiao K, Sutkeviciute I, Coin I, Bahar I, Vilardaga JP. Clark LJ, et al. Nat Chem Biol. 2020 Oct;16(10):1096-1104. doi: 10.1038/s41589-020-0567-0. Epub 2020 Jul 6. Nat Chem Biol. 2020. PMID: 32632293 Free PMC article.

Shortened Fingers and Toes: GNAS Abnormalities are Not the Only Cause.

Reyes M, Silve C, Jüppner H. Reyes M, et al. Exp Clin Endocrinol Diabetes. 2020 Oct;128(10):681-686. doi: 10.1055/a-1047-0334. Epub 2019 Dec 11. Exp Clin Endocrinol Diabetes. 2020. PMID: 31860119 Free PMC article.

PTH/PTHrP Receptor Signaling, Allostery, and Structures.

Sutkeviciute I, Clark LJ, White AD, Gardella TJ, Vilardaga JP. Sutkeviciute I, et al. Trends Endocrinol Metab. 2019 Nov;30(11):860-874. doi: 10.1016/j.tem.2019.07.011. Trends Endocrinol Metab. 2019. PMID: 31699241 Free PMC article. Review.

An Inverse Agonist Ligand of the PTH Receptor Partially Rescues Skeletal Defects in a Mouse Model of Jansen's Metaphyseal Chondrodysplasia.

Noda H, Guo J, Khatri A, Dean T, Reyes M, Armanini M, Brooks DJ, Martins JS, Schipani E, Bouxsein ML, Demay MB, Potts JT Jr, Jüppner H, Gardella TJ. Noda H, et al. J Bone Miner Res. 2020 Mar;35(3):540-549. doi: 10.1002/jbmr.3913. Epub 2019 Dec 4. J Bone Miner Res. 2020. PMID: 31693237 Free PMC article.

Salt-inducible kinases dictate parathyroid hormone 1 receptor action in bone development and remodeling.

Nishimori S, O'Meara MJ, Castro CD, Noda H, Cetinbas M, da Silva Martins J, Ayturk U, Brooks DJ, Bruce M, Nagata M, Ono W, Janton CJ, Bouxsein ML, Foretz M, Berdeaux R, Sadreyev RI, Gardella TJ, Jüppner H, Kronenberg HM, Wein MN. Nishimori S, et al. J Clin Invest. 2019 Dec 2;129(12):5187-5203. doi: 10.1172/JCI130126. J Clin Invest. 2019. PMID: 31430259 Free PMC article.

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