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ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m6A modification-mediated RNA stability control.
Gao Y, Zimmer JT, Vasic R, Liu C, Gbyli R, Zheng SJ, Patel A, Liu W, Qi Z, Li Y, Nelakanti R, Song Y, Biancon G, Xiao AZ, Slavoff S, Kibbey RG, Flavell RA, Simon MD, Tebaldi T, Li HB, Halene S. Gao Y, et al. Cell Rep. 2023 Oct 31;42(10):113163. doi: 10.1016/j.celrep.2023.113163. Epub 2023 Sep 23. Cell Rep. 2023. PMID: 37742191 Free PMC article.
Acetyl-methyllysine marks chromatin at active transcription start sites.
Lu-Culligan WJ, Connor LJ, Xie Y, Ekundayo BE, Rose BT, Machyna M, Pintado-Urbanc AP, Zimmer JT, Vock IW, Bhanu NV, King MC, Garcia BA, Bleichert F, Simon MD. Lu-Culligan WJ, et al. Nature. 2023 Oct;622(7981):173-179. doi: 10.1038/s41586-023-06565-9. Epub 2023 Sep 20. Nature. 2023. PMID: 37731000 Free PMC article.
Functional elements of the cis-regulatory lincRNA-p21.
Winkler L, Jimenez M, Zimmer JT, Williams A, Simon MD, Dimitrova N. Winkler L, et al. Cell Rep. 2022 Apr 19;39(3):110687. doi: 10.1016/j.celrep.2022.110687. Cell Rep. 2022. PMID: 35443176 Free PMC article.
Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies.
Biancon G, Joshi P, Zimmer JT, Hunck T, Gao Y, Lessard MD, Courchaine E, Barentine AES, Machyna M, Botti V, Qin A, Gbyli R, Patel A, Song Y, Kiefer L, Viero G, Neuenkirchen N, Lin H, Bewersdorf J, Simon MD, Neugebauer KM, Tebaldi T, Halene S. Biancon G, et al. Mol Cell. 2022 Mar 17;82(6):1107-1122.e7. doi: 10.1016/j.molcel.2022.02.025. Mol Cell. 2022. PMID: 35303483 Free PMC article.