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Page 1
Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation.
Tanaka S, Fukumoto Y, Nochioka K, Minami T, Kudo S, Shiba N, Takai Y, Williams CL, Liao JK, Shimokawa H. Tanaka S, et al. Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1591-600. doi: 10.1161/ATVBAHA.112.300922. Epub 2013 May 2. Arterioscler Thromb Vasc Biol. 2013. PMID: 23640485 Free PMC article. Clinical Trial.
Mitohormesis: another pleiotropic effect of statins?
Liao JK. Liao JK. Eur Heart J. 2012 Jun;33(11):1299-301. doi: 10.1093/eurheartj/ehr287. Epub 2011 Oct 6. Eur Heart J. 2012. PMID: 21979988 Free PMC article. No abstract available.
87 results