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Year | Number of Results |
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2020 | 1 |
2021 | 1 |
2022 | 2 |
2023 | 2 |
2024 | 1 |
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Cross-evaluation of E. coli's operon structures via a whole-cell model suggests alternative cellular benefits for low- versus high-expressing operons.
Cell Syst. 2024 Mar 20;15(3):227-245.e7. doi: 10.1016/j.cels.2024.02.002. Epub 2024 Feb 27.
Cell Syst. 2024.
PMID: 38417437
Whole-cell modeling of E. coli colonies enables quantification of single-cell heterogeneity in antibiotic responses.
Skalnik CJ, Cheah SY, Yang MY, Wolff MB, Spangler RK, Talman L, Morrison JH, Peirce SM, Agmon E, Covert MW.
Skalnik CJ, et al.
PLoS Comput Biol. 2023 Jun 16;19(6):e1011232. doi: 10.1371/journal.pcbi.1011232. eCollection 2023 Jun.
PLoS Comput Biol. 2023.
PMID: 37327241
Free PMC article.
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Whole-cell modeling of E. coli confirms that in vitro tRNA aminoacylation measurements are insufficient to support cell growth and predicts a positive feedback mechanism regulating arginine biosynthesis.
Choi H, Covert MW.
Choi H, et al.
Nucleic Acids Res. 2023 Jul 7;51(12):5911-5930. doi: 10.1093/nar/gkad435.
Nucleic Acids Res. 2023.
PMID: 37224536
Free PMC article.
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An expanded whole-cell model of E. coli links cellular physiology with mechanisms of growth rate control.
Ahn-Horst TA, Mille LS, Sun G, Morrison JH, Covert MW.
Ahn-Horst TA, et al.
NPJ Syst Biol Appl. 2022 Aug 19;8(1):30. doi: 10.1038/s41540-022-00242-9.
NPJ Syst Biol Appl. 2022.
PMID: 35986058
Free PMC article.
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Vivarium: an interface and engine for integrative multiscale modeling in computational biology.
Agmon E, Spangler RK, Skalnik CJ, Poole W, Peirce SM, Morrison JH, Covert MW.
Agmon E, et al.
Bioinformatics. 2022 Mar 28;38(7):1972-1979. doi: 10.1093/bioinformatics/btac049.
Bioinformatics. 2022.
PMID: 35134830
Free PMC article.
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A forecast for large-scale, predictive biology: Lessons from meteorology.
Covert MW, Gillies TE, Kudo T, Agmon E.
Covert MW, et al.
Cell Syst. 2021 Jun 16;12(6):488-496. doi: 10.1016/j.cels.2021.05.014.
Cell Syst. 2021.
PMID: 34139161
Free PMC article.
Review.
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Simultaneous cross-evaluation of heterogeneous E. coli datasets via mechanistic simulation.
Macklin DN, Ahn-Horst TA, Choi H, Ruggero NA, Carrera J, Mason JC, Sun G, Agmon E, DeFelice MM, Maayan I, Lane K, Spangler RK, Gillies TE, Paull ML, Akhter S, Bray SR, Weaver DS, Keseler IM, Karp PD, Morrison JH, Covert MW.
Macklin DN, et al.
Science. 2020 Jul 24;369(6502):eaav3751. doi: 10.1126/science.aav3751.
Science. 2020.
PMID: 32703847
Free PMC article.
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