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Merging Structural Motifs of Functionalized Amino Acids and α-Aminoamides Results in Novel Anticonvulsant Compounds with Significant Effects on Slow and Fast Inactivation of Voltage-gated Sodium Channels and in the Treatment of Neuropathic Pain.
Wang Y, Wilson SM, Brittain JM, Ripsch MS, Salomé C, Park KD, White FA, Khanna R, Kohn H. Wang Y, et al. ACS Chem Neurosci. 2011 Jun 15;2(6):317-322. doi: 10.1021/cn200024z. ACS Chem Neurosci. 2011. PMID: 21765969 Free PMC article.
Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca²⁺ channel complex.
Brittain JM, Duarte DB, Wilson SM, Zhu W, Ballard C, Johnson PL, Liu N, Xiong W, Ripsch MS, Wang Y, Fehrenbacher JC, Fitz SD, Khanna M, Park CK, Schmutzler BS, Cheon BM, Due MR, Brustovetsky T, Ashpole NM, Hudmon A, Meroueh SO, Hingtgen CM, Brustovetsky N, Ji RR, Hurley JH, Jin X, Shekhar A, Xu XM, Oxford GS, Vasko MR, White FA, Khanna R. Brittain JM, et al. Nat Med. 2011 Jun 5;17(7):822-9. doi: 10.1038/nm.2345. Nat Med. 2011. PMID: 21642979 Free PMC article.
CXCR4 signaling mediates morphine-induced tactile hyperalgesia.
Wilson NM, Jung H, Ripsch MS, Miller RJ, White FA. Wilson NM, et al. Brain Behav Immun. 2011 Mar;25(3):565-73. doi: 10.1016/j.bbi.2010.12.014. Epub 2010 Dec 28. Brain Behav Immun. 2011. PMID: 21193025 Free PMC article.
Opiate-induced hypernociception and chemokine receptors.
White F, Wilson N. White F, et al. Neuropharmacology. 2010 Jan;58(1):35-7. doi: 10.1016/j.neuropharm.2009.07.012. Epub 2009 Jul 15. Neuropharmacology. 2010. PMID: 19607847 Free PMC article.