R01-CA109355/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

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Year	Number of Results
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The CDK7 inhibitor THZ1 alters RNA polymerase dynamics at the 5' and 3' ends of genes.

Sampathi S, Acharya P, Zhao Y, Wang J, Stengel KR, Liu Q, Savona MR, Hiebert SW. Sampathi S, et al. Nucleic Acids Res. 2019 May 7;47(8):3921-3936. doi: 10.1093/nar/gkz127. Nucleic Acids Res. 2019. PMID: 30805632 Free PMC article.

BET inhibitors reduce cell size and induce reversible cell cycle arrest in AML.

Zhang S, Zhao Y, Heaster TM, Fischer MA, Stengel KR, Zhou X, Ramsey H, Zhou MM, Savona MR, Skala MC, Hiebert SW. Zhang S, et al. J Cell Biochem. 2019 May;120(5):7309-7322. doi: 10.1002/jcb.28005. Epub 2018 Nov 11. J Cell Biochem. 2019. PMID: 30417424 Free PMC article.

Deacetylase activity of histone deacetylase 3 is required for productive VDJ recombination and B-cell development.

Stengel KR, Barnett KR, Wang J, Liu Q, Hodges E, Hiebert SW, Bhaskara S. Stengel KR, et al. Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):8608-8613. doi: 10.1073/pnas.1701610114. Epub 2017 Jul 24. Proc Natl Acad Sci U S A. 2017. PMID: 28739911 Free PMC article.

High-Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML.

Zhao Y, Liu Q, Acharya P, Stengel KR, Sheng Q, Zhou X, Kwak H, Fischer MA, Bradner JE, Strickland SA, Mohan SR, Savona MR, Venters BJ, Zhou MM, Lis JT, Hiebert SW. Zhao Y, et al. Cell Rep. 2016 Aug 16;16(7):2003-16. doi: 10.1016/j.celrep.2016.07.032. Epub 2016 Aug 4. Cell Rep. 2016. PMID: 27498870 Free PMC article.

Histone Deacetylase 3 Is Required for Efficient T Cell Development.

Stengel KR, Zhao Y, Klus NJ, Kaiser JF, Gordy LE, Joyce S, Hiebert SW, Summers AR. Stengel KR, et al. Mol Cell Biol. 2015 Nov;35(22):3854-65. doi: 10.1128/MCB.00706-15. Epub 2015 Aug 31. Mol Cell Biol. 2015. PMID: 26324326 Free PMC article.

HDAC3 is essential for DNA replication in hematopoietic progenitor cells.

Summers AR, Fischer MA, Stengel KR, Zhao Y, Kaiser JF, Wells CE, Hunt A, Bhaskara S, Luzwick JW, Sampathi S, Chen X, Thompson MA, Cortez D, Hiebert SW. Summers AR, et al. J Clin Invest. 2013 Jul;123(7):3112-23. doi: 10.1172/JCI60806. Epub 2013 Jun 10. J Clin Invest. 2013. PMID: 23921131 Free PMC article.

Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma.

Wells CE, Bhaskara S, Stengel KR, Zhao Y, Sirbu B, Chagot B, Cortez D, Khabele D, Chazin WJ, Cooper A, Jacques V, Rusche J, Eischen CM, McGirt LY, Hiebert SW. Wells CE, et al. PLoS One. 2013 Jul 22;8(7):e68915. doi: 10.1371/journal.pone.0068915. Print 2013. PLoS One. 2013. PMID: 23894374 Free PMC article.

Decoding the trans-histone crosstalk: methods to analyze H2B ubiquitination, H3 methylation and their regulatory factors.

Chandrasekharan MB, Huang F, Sun ZW. Chandrasekharan MB, et al. Methods. 2011 Jul;54(3):304-14. doi: 10.1016/j.ymeth.2011.02.010. Epub 2011 Mar 8. Methods. 2011. PMID: 21392582 Free PMC article. Review.

Regulation of histone H2A and H2B deubiquitination and Xenopus development by USP12 and USP46.

Joo HY, Jones A, Yang C, Zhai L, Smith AD 4th, Zhang Z, Chandrasekharan MB, Sun ZW, Renfrow MB, Wang Y, Chang C, Wang H. Joo HY, et al. J Biol Chem. 2011 Mar 4;286(9):7190-201. doi: 10.1074/jbc.M110.158311. Epub 2010 Dec 23. J Biol Chem. 2011. PMID: 21183687 Free PMC article.

Hdac3 is essential for the maintenance of chromatin structure and genome stability.

Bhaskara S, Knutson SK, Jiang G, Chandrasekharan MB, Wilson AJ, Zheng S, Yenamandra A, Locke K, Yuan JL, Bonine-Summers AR, Wells CE, Kaiser JF, Washington MK, Zhao Z, Wagner FF, Sun ZW, Xia F, Holson EB, Khabele D, Hiebert SW. Bhaskara S, et al. Cancer Cell. 2010 Nov 16;18(5):436-47. doi: 10.1016/j.ccr.2010.10.022. Cancer Cell. 2010. PMID: 21075309 Free PMC article.

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