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2011 1
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2019 1
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Page 1
Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis.
Haak AJ, Kostallari E, Sicard D, Ligresti G, Choi KM, Caporarello N, Jones DL, Tan Q, Meridew J, Diaz Espinosa AM, Aravamudhan A, Maiers JL, Britt RD Jr, Roden AC, Pabelick CM, Prakash YS, Nouraie SM, Li X, Zhang Y, Kass DJ, Lagares D, Tager AM, Varelas X, Shah VH, Tschumperlin DJ. Haak AJ, et al. Sci Transl Med. 2019 Oct 30;11(516):eaau6296. doi: 10.1126/scitranslmed.aau6296. Sci Transl Med. 2019. PMID: 31666402 Free PMC article.
ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis.
Lagares D, Ghassemi-Kakroodi P, Tremblay C, Santos A, Probst CK, Franklin A, Santos DM, Grasberger P, Ahluwalia N, Montesi SB, Shea BS, Black KE, Knipe R, Blati M, Baron M, Wu B, Fahmi H, Gandhi R, Pardo A, Selman M, Wu J, Pelletier JP, Martel-Pelletier J, Tager AM, Kapoor M. Lagares D, et al. Nat Med. 2017 Dec;23(12):1405-1415. doi: 10.1038/nm.4419. Epub 2017 Oct 23. Nat Med. 2017. PMID: 29058717 Free PMC article.
Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis.
Shea BS, Probst CK, Brazee PL, Rotile NJ, Blasi F, Weinreb PH, Black KE, Sosnovik DE, Van Cott EM, Violette SM, Caravan P, Tager AM. Shea BS, et al. JCI Insight. 2017 May 4;2(9):e86608. doi: 10.1172/jci.insight.86608. eCollection 2017 May 4. JCI Insight. 2017. PMID: 28469072 Free PMC article.
Fibrogenic Lung Injury Induces Non-Cell-Autonomous Fibroblast Invasion.
Ahluwalia N, Grasberger PE, Mugo BM, Feghali-Bostwick C, Pardo A, Selman M, Lagares D, Tager AM. Ahluwalia N, et al. Am J Respir Cell Mol Biol. 2016 Jun;54(6):831-42. doi: 10.1165/rcmb.2015-0040OC. Am J Respir Cell Mol Biol. 2016. PMID: 26600305 Free PMC article.
24 results