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Ubiquitous points of control over regulatory T cells.
Pan F, Barbi J. Pan F, et al. J Mol Med (Berl). 2014 Jun;92(6):555-69. doi: 10.1007/s00109-014-1156-z. Epub 2014 Apr 29. J Mol Med (Berl). 2014. PMID: 24777637 Free PMC article. Review.
The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3.
Chen Z, Barbi J, Bu S, Yang HY, Li Z, Gao Y, Jinasena D, Fu J, Lin F, Chen C, Zhang J, Yu N, Li X, Shan Z, Nie J, Gao Z, Tian H, Li Y, Yao Z, Zheng Y, Park BV, Pan Z, Zhang J, Dang E, Li Z, Wang H, Luo W, Li L, Semenza GL, Zheng SG, Loser K, Tsun A, Greene MI, Pardoll DM, Pan F, Li B. Chen Z, et al. Immunity. 2013 Aug 22;39(2):272-85. doi: 10.1016/j.immuni.2013.08.006. Immunity. 2013. PMID: 23973223 Free PMC article.