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Frequent Malaria Drives Progressive Vδ2 T-Cell Loss, Dysfunction, and CD16 Up-regulation During Early Childhood.
Farrington LA, Jagannathan P, McIntyre TI, Vance HM, Bowen K, Boyle MJ, Nankya F, Wamala S, Auma A, Nalubega M, Sikyomu E, Naluwu K, Bigira V, Kapisi J, Dorsey G, Kamya MR, Feeney ME. Farrington LA, et al. J Infect Dis. 2016 May 1;213(9):1483-90. doi: 10.1093/infdis/jiv600. Epub 2015 Dec 13. J Infect Dis. 2016. PMID: 26667315 Free PMC article. Clinical Trial.
Decline of FoxP3+ Regulatory CD4 T Cells in Peripheral Blood of Children Heavily Exposed to Malaria.
Boyle MJ, Jagannathan P, Farrington LA, Eccles-James I, Wamala S, McIntyre TI, Vance HM, Bowen K, Nankya F, Auma A, Nalubega M, Sikyomu E, Naluwu K, Rek J, Katureebe A, Bigira V, Kapisi J, Tappero J, Muhindo MK, Greenhouse B, Arinaitwe E, Dorsey G, Kamya MR, Feeney ME. Boyle MJ, et al. PLoS Pathog. 2015 Jul 16;11(7):e1005041. doi: 10.1371/journal.ppat.1005041. eCollection 2015 Jul. PLoS Pathog. 2015. PMID: 26182204 Free PMC article.
Effector Phenotype of Plasmodium falciparum-Specific CD4+ T Cells Is Influenced by Both Age and Transmission Intensity in Naturally Exposed Populations.
Boyle MJ, Jagannathan P, Bowen K, McIntyre TI, Vance HM, Farrington LA, Greenhouse B, Nankya F, Rek J, Katureebe A, Arinaitwe E, Dorsey G, Kamya MR, Feeney ME. Boyle MJ, et al. J Infect Dis. 2015 Aug 1;212(3):416-25. doi: 10.1093/infdis/jiv054. Epub 2015 Feb 2. J Infect Dis. 2015. PMID: 25646355 Free PMC article.
IFNγ Responses to Pre-erythrocytic and Blood-stage Malaria Antigens Exhibit Differential Associations With Past Exposure and Subsequent Protection.
Jagannathan P, Nankya F, Stoyanov C, Eccles-James I, Sikyomu E, Naluwu K, Wamala S, Nalubega M, Briggs J, Bowen K, Bigira V, Kapisi J, Kamya MR, Dorsey G, Feeney ME. Jagannathan P, et al. J Infect Dis. 2015 Jun 15;211(12):1987-96. doi: 10.1093/infdis/jiu814. Epub 2014 Dec 17. J Infect Dis. 2015. PMID: 25520427 Free PMC article. Clinical Trial.
IFNγ/IL-10 co-producing cells dominate the CD4 response to malaria in highly exposed children.
Jagannathan P, Eccles-James I, Bowen K, Nankya F, Auma A, Wamala S, Ebusu C, Muhindo MK, Arinaitwe E, Briggs J, Greenhouse B, Tappero JW, Kamya MR, Dorsey G, Feeney ME. Jagannathan P, et al. PLoS Pathog. 2014 Jan;10(1):e1003864. doi: 10.1371/journal.ppat.1003864. Epub 2014 Jan 9. PLoS Pathog. 2014. PMID: 24415936 Free PMC article. Clinical Trial.