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Synthesis, biophysical, and pharmacological evaluation of the melanocortin agonist AST3-88: modifications of peptide backbone at Trp 7 position lead to a potent, selective, and stable ligand of the melanocortin 4 receptor (MC4R).
Singh A, Dirain ML, Wilczynski A, Chen C, Gosnell BA, Levine AS, Edison AS, Haskell-Luevano C. Singh A, et al. ACS Chem Neurosci. 2014 Oct 15;5(10):1020-31. doi: 10.1021/cn5000953. Epub 2014 Aug 26. ACS Chem Neurosci. 2014. PMID: 25141170 Free PMC article.
The contribution of brain reward circuits to the obesity epidemic.
Stice E, Figlewicz DP, Gosnell BA, Levine AS, Pratt WE. Stice E, et al. Neurosci Biobehav Rev. 2013 Nov;37(9 Pt A):2047-58. doi: 10.1016/j.neubiorev.2012.12.001. Epub 2012 Dec 10. Neurosci Biobehav Rev. 2013. PMID: 23237885 Free PMC article. Review.
Reward systems and food intake: role of opioids.
Gosnell BA, Levine AS. Gosnell BA, et al. Int J Obes (Lond). 2009 Jun;33 Suppl 2:S54-8. doi: 10.1038/ijo.2009.73. Int J Obes (Lond). 2009. PMID: 19528981 Review.
11 results