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A Pan-Histone Deacetylase Inhibitor Enhances the Antitumor Activity of B7-H3-Specific CAR T Cells in Solid Tumors.
Lei X, Ou Z, Yang Z, Zhong J, Zhu Y, Tian J, Wu J, Deng H, Lin X, Peng Y, Li B, He L, Tu Z, Chen W, Li Q, Liu N, Zhang H, Wang Z, Fang Z, Yamada T, Lv X, Tian T, Pan G, Wu F, Xiao L, Zhang L, Cai T, Wang X, Tannous BA, Li J, Kontos F, Ferrone S, Fan S. Lei X, et al. Clin Cancer Res. 2021 Jul 1;27(13):3757-3771. doi: 10.1158/1078-0432.CCR-20-2487. Epub 2021 Apr 2. Clin Cancer Res. 2021. PMID: 33811153 Free PMC article.
Modifications to the Framework Regions Eliminate Chimeric Antigen Receptor Tonic Signaling.
Landoni E, Fucá G, Wang J, Chirasani VR, Yao Z, Dukhovlinova E, Ferrone S, Savoldo B, Hong LK, Shou P, Musio S, Padelli F, Finocchiaro G, Droste M, Kuhlman B, Shamshiev A, Pellegatta S, Dokholyan NV, Dotti G. Landoni E, et al. Cancer Immunol Res. 2021 Apr;9(4):441-453. doi: 10.1158/2326-6066.CIR-20-0451. Epub 2021 Feb 5. Cancer Immunol Res. 2021. PMID: 33547226 Free PMC article.
CSPG4-Specific CAR.CIK Lymphocytes as a Novel Therapy for the Treatment of Multiple Soft-Tissue Sarcoma Histotypes.
Leuci V, Donini C, Grignani G, Rotolo R, Mesiano G, Fiorino E, Gammaitoni L, D'Ambrosio L, Merlini A, Landoni E, Medico E, Capellero S, Giraudo L, Cattaneo G, Iaia I, Pignochino Y, Basiricò M, Vigna E, Pisacane A, Fagioli F, Ferrone S, Aglietta M, Dotti G, Sangiolo D. Leuci V, et al. Clin Cancer Res. 2020 Dec 1;26(23):6321-6334. doi: 10.1158/1078-0432.CCR-20-0357. Epub 2020 Sep 8. Clin Cancer Res. 2020. PMID: 32900797 Free PMC article.
15 results