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The emerging nontraditional roles for tau in the brain.
Cytoskeleton (Hoboken). 2024 Jan;81(1):89-94. doi: 10.1002/cm.21811. Epub 2023 Dec 8.
Cytoskeleton (Hoboken). 2024.
PMID: 38063261
No abstract available.
Identification of a reciprocal negative feedback loop between tau-modifying proteins MARK2 kinase and CBP acetyltransferase.
Tabassum Z, Tseng JH, Isemann C, Tian X, Chen Y, Herring LE, Cohen TJ.
Tabassum Z, et al.
J Biol Chem. 2022 Jun;298(6):101977. doi: 10.1016/j.jbc.2022.101977. Epub 2022 Apr 22.
J Biol Chem. 2022.
PMID: 35469920
Free PMC article.
Item in Clipboard
Identification of distinct N-glycosylation patterns on extracellular vesicles from small-cell and non-small-cell lung cancer cells.
Kondo K, Harada Y, Nakano M, Suzuki T, Fukushige T, Hanzawa K, Yagi H, Takagi K, Mizuno K, Miyamoto Y, Taniguchi N, Kato K, Kanekura T, Dohmae N, Machida K, Maruyama I, Inoue H.
Kondo K, et al.
J Biol Chem. 2022 Jun;298(6):101950. doi: 10.1016/j.jbc.2022.101950. Epub 2022 Apr 18.
J Biol Chem. 2022.
PMID: 35447118
Free PMC article.
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Tau seeds are subject to aberrant modifications resulting in distinct signatures.
Tseng JH, Ajit A, Tabassum Z, Patel N, Tian X, Chen Y, Prevatte AW, Ling K, Rigo F, Meeker RB, Herring LE, Cohen TJ.
Tseng JH, et al.
Cell Rep. 2021 Apr 27;35(4):109037. doi: 10.1016/j.celrep.2021.109037.
Cell Rep. 2021.
PMID: 33910013
Free PMC article.
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An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline.
Trzeciakiewicz H, Ajit D, Tseng JH, Chen Y, Ajit A, Tabassum Z, Lobrovich R, Peterson C, Riddick NV, Itano MS, Tripathy A, Moy SS, Lee VMY, Trojanowski JQ, Irwin DJ, Cohen TJ.
Trzeciakiewicz H, et al.
Nat Commun. 2020 Nov 2;11(1):5522. doi: 10.1038/s41467-020-19317-4.
Nat Commun. 2020.
PMID: 33139698
Free PMC article.
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A unique tau conformation generated by an acetylation-mimic substitution modulates P301S-dependent tau pathology and hyperphosphorylation.
Ajit D, Trzeciakiewicz H, Tseng JH, Wander CM, Chen Y, Ajit A, King DP, Cohen TJ.
Ajit D, et al.
J Biol Chem. 2019 Nov 8;294(45):16698-16711. doi: 10.1074/jbc.RA119.009674. Epub 2019 Sep 22.
J Biol Chem. 2019.
PMID: 31543505
Free PMC article.
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