R35 HL144998/HL/NHLBI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2019	4
2020	4
2021	5
2022	4
2023	1
2024	2

1

Mechanisms of RBM20 Cardiomyopathy: Insights From Model Systems.

Gregorich ZR, Zhang Y, Kamp TJ, Granzier HL, Guo W. Gregorich ZR, et al. Circ Genom Precis Med. 2024 Feb;17(1):e004355. doi: 10.1161/CIRCGEN.123.004355. Epub 2024 Jan 30. Circ Genom Precis Med. 2024. PMID: 38288598 Review.

2

In vivo gene editing of CAMKIID: out with the bad and in with the good.

Smith JE 3rd, Granzier H. Smith JE 3rd, et al. J Clin Invest. 2024 Jan 2;134(1):e176672. doi: 10.1172/JCI176672. J Clin Invest. 2024. PMID: 38165033 Free PMC article.

3

Myosin-binding protein H-like regulates myosin-binding protein distribution and function in atrial cardiomyocytes.

Barefield DY, Tonino P, Woulfe KC, Rahmanseresht S, O'Leary TS, Burnham HV, Wasserstrom JA, Kirk JA, Previs MJ, Granzier HL, McNally EM. Barefield DY, et al. Proc Natl Acad Sci U S A. 2023 Dec 19;120(51):e2314920120. doi: 10.1073/pnas.2314920120. Epub 2023 Dec 13. Proc Natl Acad Sci U S A. 2023. PMID: 38091294

4

HDAC6 modulates myofibril stiffness and diastolic function of the heart.

Lin YH, Major JL, Liebner T, Hourani Z, Travers JG, Wennersten SA, Haefner KR, Cavasin MA, Wilson CE, Jeong MY, Han Y, Gotthardt M, Ferguson SK, Ambardekar AV, Lam MP, Choudhary C, Granzier HL, Woulfe KC, McKinsey TA. Lin YH, et al. J Clin Invest. 2022 May 16;132(10):e148333. doi: 10.1172/JCI148333. J Clin Invest. 2022. PMID: 35575093 Free PMC article.

5

RBM20 phosphorylation and its role in nucleocytoplasmic transport and cardiac pathogenesis.

Zhang Y, Wang C, Sun M, Jin Y, Braz CU, Khatib H, Hacker TA, Liss M, Gotthardt M, Granzier H, Ge Y, Guo W. Zhang Y, et al. FASEB J. 2022 May;36(5):e22302. doi: 10.1096/fj.202101811RR. FASEB J. 2022. PMID: 35394688 Free PMC article.

6

RBM20^S639G mutation is a high genetic risk factor for premature death through RNA-protein condensates.

Wang C, Zhang Y, Methawasin M, Braz CU, Gao-Hu J, Yang B, Strom J, Gohlke J, Hacker T, Khatib H, Granzier H, Guo W. Wang C, et al. J Mol Cell Cardiol. 2022 Apr;165:115-129. doi: 10.1016/j.yjmcc.2022.01.004. Epub 2022 Jan 15. J Mol Cell Cardiol. 2022. PMID: 35041844 Free PMC article.

7

Shortening the thick filament by partial deletion of titin's C-zone alters cardiac function by reducing the operating sarcomere length range.

Methawasin M, Farman GP, Granzier-Nakajima S, Strom J, Kiss B, Smith JE 3rd, Granzier H. Methawasin M, et al. J Mol Cell Cardiol. 2022 Apr;165:103-114. doi: 10.1016/j.yjmcc.2022.01.002. Epub 2022 Jan 11. J Mol Cell Cardiol. 2022. PMID: 35031281 Free PMC article.

8

Titin M-line insertion sequence 7 is required for proper cardiac function in mice.

Biquand A, Spinozzi S, Tonino P, Cosette J, Strom J, Elbeck Z, Knöll R, Granzier H, Lostal W, Richard I. Biquand A, et al. J Cell Sci. 2021 Sep 15;134(18):jcs258684. doi: 10.1242/jcs.258684. Epub 2021 Sep 17. J Cell Sci. 2021. PMID: 34401916 Free PMC article.

9

Muscle ankyrin repeat protein 1 (MARP1) locks titin to the sarcomeric thin filament and is a passive force regulator.

van der Pijl RJ, van den Berg M, van de Locht M, Shen S, Bogaards SJP, Conijn S, Langlais P, Hooijman PE, Labeit S, Heunks LMA, Granzier H, Ottenheijm CAC. van der Pijl RJ, et al. J Gen Physiol. 2021 Jul 5;153(7):e202112925. doi: 10.1085/jgp.202112925. Epub 2021 Jun 21. J Gen Physiol. 2021. PMID: 34152365 Free PMC article.

10

Pathogenic variants in TNNC2 cause congenital myopathy due to an impaired force response to calcium.

van de Locht M, Donkervoort S, de Winter JM, Conijn S, Begthel L, Kusters B, Mohassel P, Hu Y, Medne L, Quinn C, Moore SA, Foley AR, Seo G, Hwee DT, Malik FI, Irving T, Ma W, Granzier HL, Kamsteeg EJ, Immadisetty K, Kekenes-Huskey P, Pinto JR, Voermans N, Bönnemann CG, Ottenheijm CA. van de Locht M, et al. J Clin Invest. 2021 May 3;131(9):e145700. doi: 10.1172/JCI145700. J Clin Invest. 2021. PMID: 33755597 Free PMC article.

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