R37 DK052778/DK/NIDDK NIH HHS/United States[Grants and Funding] - Search Results

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Subject: R37 DK052778/DK/NIDDK NIH HHS/United States[Grant - PubMed

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Results by year

Year	Number of Results
2008	1
2009	3
2010	5
2011	2
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2013	2
2014	1
2015	2
2016	1
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2018	1
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2024	0

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Mist1+ gastric isthmus stem cells are regulated by Wnt5a and expand in response to injury and inflammation in mice.

Nienhüser H, Kim W, Malagola E, Ruan T, Valenti G, Middelhoff M, Bass A, Der CJ, Hayakawa Y, Wang TC. Nienhüser H, et al. Gut. 2021 Apr;70(4):654-665. doi: 10.1136/gutjnl-2020-320742. Epub 2020 Jul 24. Gut. 2021. PMID: 32709613 Free PMC article.

Hormonal Suppression of Stem Cells Inhibits Symmetric Cell Division and Gastric Tumorigenesis.

Chang W, Wang H, Kim W, Liu Y, Deng H, Liu H, Jiang Z, Niu Z, Sheng W, Nápoles OC, Sun Y, Xu J, Sepulveda A, Hayakawa Y, Bass AJ, Wang TC. Chang W, et al. Cell Stem Cell. 2020 May 7;26(5):739-754.e8. doi: 10.1016/j.stem.2020.01.020. Epub 2020 Mar 5. Cell Stem Cell. 2020. PMID: 32142681 Free PMC article.

Evaluation of Lineage Changes in the Gastric Mucosa Following Infection With Helicobacter pylori and Specified Intestinal Flora in INS-GAS Mice.

Pinzon-Guzman C, Meyer AR, Wise R, Choi E, Muthupalani S, Wang TC, Fox JG, Goldenring JR. Pinzon-Guzman C, et al. J Histochem Cytochem. 2019 Jan;67(1):53-63. doi: 10.1369/0022155418785621. Epub 2018 Jul 3. J Histochem Cytochem. 2019. PMID: 29969055 Free PMC article.

The G-protein coupled receptor 56, expressed in colonic stem and cancer cells, binds progastrin to promote proliferation and carcinogenesis.

Jin G, Sakitani K, Wang H, Jin Y, Dubeykovskiy A, Worthley DL, Tailor Y, Wang TC. Jin G, et al. Oncotarget. 2017 Jun 20;8(25):40606-40619. doi: 10.18632/oncotarget.16506. Oncotarget. 2017. PMID: 28380450 Free PMC article.

Gastrin and upper GI cancers.

Hayakawa Y, Chang W, Jin G, Wang TC. Hayakawa Y, et al. Curr Opin Pharmacol. 2016 Dec;31:31-37. doi: 10.1016/j.coph.2016.08.013. Epub 2016 Aug 31. Curr Opin Pharmacol. 2016. PMID: 27591354 Review.

Gastrin stimulates a cholecystokinin-2-receptor-expressing cardia progenitor cell and promotes progression of Barrett's-like esophagus.

Lee Y, Urbanska AM, Hayakawa Y, Wang H, Au AS, Luna AM, Chang W, Jin G, Bhagat G, Abrams JA, Friedman RA, Varro A, Wang KK, Boyce M, Rustgi AK, Sepulveda AR, Quante M, Wang TC. Lee Y, et al. Oncotarget. 2017 Jan 3;8(1):203-214. doi: 10.18632/oncotarget.10667. Oncotarget. 2017. PMID: 27448962 Free PMC article.

Krt19(+)/Lgr5(-) Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine.

Asfaha S, Hayakawa Y, Muley A, Stokes S, Graham TA, Ericksen RE, Westphalen CB, von Burstin J, Mastracci TL, Worthley DL, Guha C, Quante M, Rustgi AK, Wang TC. Asfaha S, et al. Cell Stem Cell. 2015 Jun 4;16(6):627-38. doi: 10.1016/j.stem.2015.04.013. Cell Stem Cell. 2015. PMID: 26046762 Free PMC article.

CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis.

Hayakawa Y, Jin G, Wang H, Chen X, Westphalen CB, Asfaha S, Renz BW, Ariyama H, Dubeykovskaya ZA, Takemoto Y, Lee Y, Muley A, Tailor Y, Chen D, Muthupalani S, Fox JG, Shulkes A, Worthley DL, Takaishi S, Wang TC. Hayakawa Y, et al. Gut. 2015 Apr;64(4):544-53. doi: 10.1136/gutjnl-2014-307190. Epub 2014 Jun 20. Gut. 2015. PMID: 24951258 Free PMC article.

Progastrin stimulates colonic cell proliferation via CCK2R- and β-arrestin-dependent suppression of BMP2.

Jin G, Westphalen CB, Hayakawa Y, Worthley DL, Asfaha S, Yang X, Chen X, Si Y, Wang H, Tailor Y, Friedman RA, Wang TC. Jin G, et al. Gastroenterology. 2013 Oct;145(4):820-30.e10. doi: 10.1053/j.gastro.2013.07.034. Epub 2013 Jul 25. Gastroenterology. 2013. PMID: 23891976 Free PMC article.

Progastrin-induced secretion of insulin-like growth factor 2 from colonic myofibroblasts stimulates colonic epithelial proliferation in mice.

Duckworth CA, Clyde D, Worthley DL, Wang TC, Varro A, Pritchard DM. Duckworth CA, et al. Gastroenterology. 2013 Jul;145(1):197-208.e3. doi: 10.1053/j.gastro.2013.03.012. Epub 2013 Mar 19. Gastroenterology. 2013. PMID: 23523669 Free PMC article.

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