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Juvenile exposure to anthracyclines impairs cardiac progenitor cell function and vascularization resulting in greater susceptibility to stress-induced myocardial injury in adult mice.
Huang C, Zhang X, Ramil JM, Rikka S, Kim L, Lee Y, Gude NA, Thistlethwaite PA, Sussman MA, Gottlieb RA, Gustafsson AB. Huang C, et al. Circulation. 2010 Feb 9;121(5):675-83. doi: 10.1161/CIRCULATIONAHA.109.902221. Epub 2010 Jan 25. Circulation. 2010. PMID: 20100968 Free PMC article.
Cardiac progenitor cell cycling stimulated by pim-1 kinase.
Cottage CT, Bailey B, Fischer KM, Avitabile D, Collins B, Tuck S, Quijada P, Gude N, Alvarez R, Muraski J, Sussman MA. Cottage CT, et al. Circ Res. 2010 Mar 19;106(5):891-901. doi: 10.1161/CIRCRESAHA.109.208629. Epub 2010 Jan 14. Circ Res. 2010. PMID: 20075333 Free PMC article.