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2010 3
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Page 1
Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics.
Tucholski T, Cai W, Gregorich ZR, Bayne EF, Mitchell SD, McIlwain SJ, de Lange WJ, Wrobbel M, Karp H, Hite Z, Vikhorev PG, Marston SB, Lal S, Li A, Dos Remedios C, Kohmoto T, Hermsen J, Ralphe JC, Kamp TJ, Moss RL, Ge Y. Tucholski T, et al. Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):24691-24700. doi: 10.1073/pnas.2006764117. Epub 2020 Sep 23. Proc Natl Acad Sci U S A. 2020. PMID: 32968017 Free PMC article.
The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM.
Piroddi N, Witjas-Paalberends ER, Ferrara C, Ferrantini C, Vitale G, Scellini B, Wijnker PJM, Sequiera V, Dooijes D, Dos Remedios C, Schlossarek S, Leung MC, Messer A, Ward DG, Biggeri A, Tesi C, Carrier L, Redwood CS, Marston SB, van der Velden J, Poggesi C. Piroddi N, et al. J Gen Physiol. 2019 Jan 7;151(1):18-29. doi: 10.1085/jgp.201812160. Epub 2018 Dec 21. J Gen Physiol. 2019. PMID: 30578328 Free PMC article.
Isogenic Pairs of hiPSC-CMs with Hypertrophic Cardiomyopathy/LVNC-Associated ACTC1 E99K Mutation Unveil Differential Functional Deficits.
Smith JGW, Owen T, Bhagwan JR, Mosqueira D, Scott E, Mannhardt I, Patel A, Barriales-Villa R, Monserrat L, Hansen A, Eschenhagen T, Harding SE, Marston S, Denning C. Smith JGW, et al. Stem Cell Reports. 2018 Nov 13;11(5):1226-1243. doi: 10.1016/j.stemcr.2018.10.006. Epub 2018 Nov 1. Stem Cell Reports. 2018. PMID: 30392975 Free PMC article.
64 results