Radzisheuskaya A - Search Results

1

Generation of locus-specific degradable tag knock-ins in mouse and human cell lines.

Damhofer H, Radzisheuskaya A, Helin K. Damhofer H, et al. Among authors: radzisheuskaya a. STAR Protoc. 2021 Jun 2;2(2):100575. doi: 10.1016/j.xpro.2021.100575. eCollection 2021 Jun 18. STAR Protoc. 2021. PMID: 34151298 Free PMC article.

2

Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development.

Pedersen MT, Kooistra SM, Radzisheuskaya A, Laugesen A, Johansen JV, Hayward DG, Nilsson J, Agger K, Helin K. Pedersen MT, et al. Among authors: radzisheuskaya a. EMBO J. 2016 Jul 15;35(14):1550-64. doi: 10.15252/embj.201593317. Epub 2016 Jun 6. EMBO J. 2016. PMID: 27266524 Free PMC article.

3

Optimizing sgRNA position markedly improves the efficiency of CRISPR/dCas9-mediated transcriptional repression.

Radzisheuskaya A, Shlyueva D, Müller I, Helin K. Radzisheuskaya A, et al. Nucleic Acids Res. 2016 Oct 14;44(18):e141. doi: 10.1093/nar/gkw583. Epub 2016 Jun 28. Nucleic Acids Res. 2016. PMID: 27353328 Free PMC article.

4

PRMT5 methylome profiling uncovers a direct link to splicing regulation in acute myeloid leukemia.

Radzisheuskaya A, Shliaha PV, Grinev V, Lorenzini E, Kovalchuk S, Shlyueva D, Gorshkov V, Hendrickson RC, Jensen ON, Helin K. Radzisheuskaya A, et al. Nat Struct Mol Biol. 2019 Nov;26(11):999-1012. doi: 10.1038/s41594-019-0313-z. Epub 2019 Oct 14. Nat Struct Mol Biol. 2019. PMID: 31611688 Free PMC article.

5

A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2.

Garland W, Comet I, Wu M, Radzisheuskaya A, Rib L, Vitting-Seerup K, Lloret-Llinares M, Sandelin A, Helin K, Jensen TH. Garland W, et al. Among authors: radzisheuskaya a. Cell Rep. 2019 Nov 12;29(7):1800-1811.e6. doi: 10.1016/j.celrep.2019.10.011. Cell Rep. 2019. PMID: 31722198 Free PMC article.

6

PRMT5 Inhibition Modulates E2F1 Methylation and Gene-Regulatory Networks Leading to Therapeutic Efficacy in JAK2^V617F-Mutant MPN.

Pastore F, Bhagwat N, Pastore A, Radzisheuskaya A, Karzai A, Krishnan A, Li B, Bowman RL, Xiao W, Viny AD, Zouak A, Park YC, Cordner KB, Braunstein S, Maag JL, Grego A, Mehta J, Wang M, Lin H, Durham BH, Koche RP, Rampal RK, Helin K, Scherle P, Vaddi K, Levine RL. Pastore F, et al. Among authors: radzisheuskaya a. Cancer Discov. 2020 Nov;10(11):1742-1757. doi: 10.1158/2159-8290.CD-20-0026. Epub 2020 Jul 15. Cancer Discov. 2020. PMID: 32669286 Free PMC article.

7

Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis.

Radzisheuskaya A, Shliaha PV, Grinev VV, Shlyueva D, Damhofer H, Koche R, Gorshkov V, Kovalchuk S, Zhan Y, Rodriguez KL, Johnstone AL, Keogh MC, Hendrickson RC, Jensen ON, Helin K. Radzisheuskaya A, et al. Mol Cell. 2021 Apr 15;81(8):1749-1765.e8. doi: 10.1016/j.molcel.2021.02.012. Epub 2021 Mar 2. Mol Cell. 2021. PMID: 33657400 Free PMC article.

8

MPP8 is essential for sustaining self-renewal of ground-state pluripotent stem cells.

Müller I, Moroni AS, Shlyueva D, Sahadevan S, Schoof EM, Radzisheuskaya A, Højfeldt JW, Tatar T, Koche RP, Huang C, Helin K. Müller I, et al. Among authors: radzisheuskaya a. Nat Commun. 2021 May 24;12(1):3034. doi: 10.1038/s41467-021-23308-4. Nat Commun. 2021. PMID: 34031396 Free PMC article.

9

An alternative NURF complex sustains acute myeloid leukemia by regulating the accessibility of insulator regions.

Radzisheuskaya A, Peña-Rømer I, Lorenzini E, Koche R, Zhan Y, Shliaha PV, Cooper AJ, Fan Z, Shlyueva D, Johansen JV, Hendrickson RC, Helin K. Radzisheuskaya A, et al. EMBO J. 2023 Dec 11;42(24):e114221. doi: 10.15252/embj.2023114221. Epub 2023 Nov 21. EMBO J. 2023. PMID: 37987160 Free PMC article.

10

A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages.

Radzisheuskaya A, Chia Gle B, dos Santos RL, Theunissen TW, Castro LF, Nichols J, Silva JC. Radzisheuskaya A, et al. Nat Cell Biol. 2013 Jun;15(6):579-90. doi: 10.1038/ncb2742. Epub 2013 Apr 30. Nat Cell Biol. 2013. PMID: 23629142 Free PMC article.

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