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Tim-3 mediates T cell trogocytosis to limit antitumor immunity.
Pagliano O, Morrison RM, Chauvin JM, Banerjee H, Davar D, Ding Q, Tanegashima T, Gao W, Chakka SR, DeBlasio R, Lowin A, Kara K, Ka M, Zidi B, Amin R, Raphael I, Zhang S, Watkins SC, Sander C, Kirkwood JM, Bosenberg M, Anderson AC, Kuchroo VK, Kane LP, Korman AJ, Rajpal A, West SM, Han M, Bee C, Deng X, Schebye XM, Strop P, Zarour HM. Pagliano O, et al. Among authors: rajpal a. J Clin Invest. 2022 May 2;132(9):e152864. doi: 10.1172/JCI152864. J Clin Invest. 2022. PMID: 35316223 Free PMC article.
VISTA is an acidic pH-selective ligand for PSGL-1.
Johnston RJ, Su LJ, Pinckney J, Critton D, Boyer E, Krishnakumar A, Corbett M, Rankin AL, Dibella R, Campbell L, Martin GH, Lemar H, Cayton T, Huang RY, Deng X, Nayeem A, Chen H, Ergel B, Rizzo JM, Yamniuk AP, Dutta S, Ngo J, Shorts AO, Ramakrishnan R, Kozhich A, Holloway J, Fang H, Wang YK, Yang Z, Thiam K, Rakestraw G, Rajpal A, Sheppard P, Quigley M, Bahjat KS, Korman AJ. Johnston RJ, et al. Among authors: rajpal a. Nature. 2019 Oct;574(7779):565-570. doi: 10.1038/s41586-019-1674-5. Epub 2019 Oct 23. Nature. 2019. PMID: 31645726
Antibody blockade of CD96 by distinct molecular mechanisms.
Lee PS, Chau B, Barman I, Bee C, Jashnani A, Hogan JM, Aguilar B, Dollinger G, Rajpal A, Strop P. Lee PS, et al. Among authors: rajpal a. MAbs. 2021 Jan-Dec;13(1):1979800. doi: 10.1080/19420862.2021.1979800. MAbs. 2021. PMID: 34595996 Free PMC article.
Improved therapeutic index of an acidic pH-selective antibody.
Lee PS, MacDonald KG, Massi E, Chew PV, Bee C, Perkins P, Chau B, Thudium K, Lohre J, Nandi P, Deyanova EG, Barman I, Gudmundsson O, Dollinger G, Sproul T, Engelhardt JJ, Strop P, Rajpal A. Lee PS, et al. Among authors: rajpal a. MAbs. 2022 Jan-Dec;14(1):2024642. doi: 10.1080/19420862.2021.2024642. MAbs. 2022. PMID: 35192429 Free PMC article.
107 results