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Necroptosis contributes to chronic inflammation and fibrosis in aging liver.
Mohammed S, Thadathil N, Selvarani R, Nicklas EH, Wang D, Miller BF, Richardson A, Deepa SS. Mohammed S, et al. Among authors: selvarani r. Aging Cell. 2021 Dec;20(12):e13512. doi: 10.1111/acel.13512. Epub 2021 Nov 11. Aging Cell. 2021. PMID: 34761505 Free PMC article.
Senolytic treatment reduces cell senescence and necroptosis in Sod1 knockout mice that is associated with reduced inflammation and hepatocellular carcinoma.
Thadathil N, Selvarani R, Mohammed S, Nicklas EH, Tran AL, Kamal M, Luo W, Brown JL, Lawrence MM, Borowik AK, Miller BF, Van Remmen H, Richardson A, Deepa SS. Thadathil N, et al. Among authors: selvarani r. Aging Cell. 2022 Aug;21(8):e13676. doi: 10.1111/acel.13676. Epub 2022 Jul 23. Aging Cell. 2022. PMID: 35869934 Free PMC article.
A Genetically Heterogeneous Rat Model with Divergent Mitochondrial Genomes.
Sathiaseelan R, Ahn B, Stout MB, Logan S, Wanagat J, Nguyen HVM, Hord NG, Vandiver AR, Selvarani R, Ranjit R, Yarbrough H, Masingale A, Miller BF, Wolf RF, Austad SN, Richardson A. Sathiaseelan R, et al. Among authors: selvarani r. J Gerontol A Biol Sci Med Sci. 2023 May 11;78(5):771-779. doi: 10.1093/gerona/glad056. J Gerontol A Biol Sci Med Sci. 2023. PMID: 36762848 Free PMC article.
Intracellular iron accumulation facilitates mycobacterial infection in old mouse macrophages.
Kotey SK, Tan X, Fleming O, Kasiraju RR, Dagnell AL, Van Pelt KN, Rogers J, Hartson SD, Thadathil N, Selvarani R, Ranjit R, Logan S, Deepa SS, Richardson A, Cheng Y. Kotey SK, et al. Among authors: selvarani r. Geroscience. 2024 Apr;46(2):2739-2754. doi: 10.1007/s11357-023-01048-1. Epub 2023 Dec 30. Geroscience. 2024. PMID: 38159133 Free PMC article.
Non-Necroptotic Roles of MLKL in Diet-Induced Obesity, Liver Pathology, and Insulin Sensitivity: Insights from a High-Fat, High-Fructose, High-Cholesterol Diet Mouse Model.
Ohene-Marfo P, Nguyen HVM, Mohammed S, Thadathil N, Tran A, Nicklas EH, Wang D, Selvarani R, Farriester JW, Varshney R, Kinter M, Richardson A, Rudolph MC, Deepa SS. Ohene-Marfo P, et al. Among authors: selvarani r. Int J Mol Sci. 2024 Feb 28;25(5):2813. doi: 10.3390/ijms25052813. Int J Mol Sci. 2024. PMID: 38474061 Free PMC article.
Non-Necroptotic Roles of MLKL in Diet-Induced Obesity, Liver Pathology, and Insulin Sensitivity: Insights from a High Fat, High Fructose, High Cholesterol Diet Mouse Model.
Ohene-Marfo P, Nguyen HVM, Mohammed S, Thadathil N, Tran A, Nicklas EH, Wang D, Selvarani R, Farriester J, Varshney R, Kinter M, Richardson A, Rudolph M, Deepa SS. Ohene-Marfo P, et al. Among authors: selvarani r. bioRxiv [Preprint]. 2024 Jan 11:2024.01.10.575102. doi: 10.1101/2024.01.10.575102. bioRxiv. 2024. PMID: 38260537 Free PMC article. Updated. Preprint.