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Single-molecule visualization of DNA G-quadruplex formation in live cells.
Di Antonio M, Ponjavic A, Radzevičius A, Ranasinghe RT, Catalano M, Zhang X, Shen J, Needham LM, Lee SF, Klenerman D, Balasubramanian S. Di Antonio M, et al. Among authors: ranasinghe rt. Nat Chem. 2020 Sep;12(9):832-837. doi: 10.1038/s41557-020-0506-4. Epub 2020 Jul 20. Nat Chem. 2020. PMID: 32690897 Free PMC article.
Single molecule fluorescence under conditions of fast flow.
Horrocks MH, Li H, Shim JU, Ranasinghe RT, Clarke RW, Huck WT, Abell C, Klenerman D. Horrocks MH, et al. Among authors: ranasinghe rt. Anal Chem. 2012 Jan 3;84(1):179-85. doi: 10.1021/ac202313d. Epub 2011 Dec 6. Anal Chem. 2012. PMID: 22147688
Highly rapid amplification-free and quantitative DNA imaging assay.
Klamp T, Camps M, Nieto B, Guasch F, Ranasinghe RT, Wiedemann J, Petrášek Z, Schwille P, Klenerman D, Sauer M. Klamp T, et al. Among authors: ranasinghe rt. Sci Rep. 2013;3:1852. doi: 10.1038/srep01852. Sci Rep. 2013. PMID: 23677392 Free PMC article.
Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping.
Bongiovanni MN, Godet J, Horrocks MH, Tosatto L, Carr AR, Wirthensohn DC, Ranasinghe RT, Lee JE, Ponjavic A, Fritz JV, Dobson CM, Klenerman D, Lee SF. Bongiovanni MN, et al. Among authors: ranasinghe rt. Nat Commun. 2016 Dec 8;7:13544. doi: 10.1038/ncomms13544. Nat Commun. 2016. PMID: 27929085 Free PMC article.
Detecting RNA base methylations in single cells by in situ hybridization.
Ranasinghe RT, Challand MR, Ganzinger KA, Lewis BW, Softley C, Schmied WH, Horrocks MH, Shivji N, Chin JW, Spencer J, Klenerman D. Ranasinghe RT, et al. Nat Commun. 2018 Feb 13;9(1):655. doi: 10.1038/s41467-017-02714-7. Nat Commun. 2018. PMID: 29440632 Free PMC article.
α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson's disease.
Ludtmann MHR, Angelova PR, Horrocks MH, Choi ML, Rodrigues M, Baev AY, Berezhnov AV, Yao Z, Little D, Banushi B, Al-Menhali AS, Ranasinghe RT, Whiten DR, Yapom R, Dolt KS, Devine MJ, Gissen P, Kunath T, Jaganjac M, Pavlov EV, Klenerman D, Abramov AY, Gandhi S. Ludtmann MHR, et al. Among authors: ranasinghe rt. Nat Commun. 2018 Jun 12;9(1):2293. doi: 10.1038/s41467-018-04422-2. Nat Commun. 2018. PMID: 29895861 Free PMC article.
Nanoscopic Characterisation of Individual Endogenous Protein Aggregates in Human Neuronal Cells.
Whiten DR, Zuo Y, Calo L, Choi ML, De S, Flagmeier P, Wirthensohn DC, Kundel F, Ranasinghe RT, Sanchez SE, Athauda D, Lee SF, Dobson CM, Gandhi S, Spillantini MG, Klenerman D, Horrocks MH. Whiten DR, et al. Among authors: ranasinghe rt. Chembiochem. 2018 Oct 4;19(19):2033-2038. doi: 10.1002/cbic.201800209. Epub 2018 Sep 11. Chembiochem. 2018. PMID: 30051958 Free PMC article.
Imaging rRNA Methylation in Bacteria by MR-FISH.
Ganzinger KA, Challand MR, Spencer J, Klenerman D, Ranasinghe RT. Ganzinger KA, et al. Among authors: ranasinghe rt. Methods Mol Biol. 2019;2038:89-107. doi: 10.1007/978-1-4939-9674-2_7. Methods Mol Biol. 2019. PMID: 31407280
22 results