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Novel tetrahydropyrido[1,2-a]isoindolone derivatives (valmerins): potent cyclin-dependent kinase/glycogen synthase kinase 3 inhibitors with antiproliferative activities and antitumor effects in human tumor xenografts.
Boulahjar R, Ouach A, Matteo C, Bourg S, Ravache M, le Guével R, Marionneau S, Oullier T, Lozach O, Meijer L, Guguen-Guillouzo C, Lazar S, Akssira M, Troin Y, Guillaumet G, Routier S. Boulahjar R, et al. Among authors: ravache m. J Med Chem. 2012 Nov 26;55(22):9589-606. doi: 10.1021/jm3008536. Epub 2012 Nov 1. J Med Chem. 2012. PMID: 23083119
Synthetic Development of New 3-(4-Arylmethylamino)butyl-5-arylidene-rhodanines under Microwave Irradiation and Their Effects on Tumor Cell Lines and against Protein Kinases.
Dago CD, Ambeu CN, Coulibaly WK, Békro YA, Mamyrbékova J, Defontaine A, Baratte B, Bach S, Ruchaud S, Guével RL, Ravache M, Corlu A, Bazureau JP. Dago CD, et al. Among authors: ravache m. Molecules. 2015 Jul 8;20(7):12412-35. doi: 10.3390/molecules200712412. Molecules. 2015. PMID: 26184130 Free PMC article.