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Derivatives of (-)-7-methyl-2-(5-(pyridinyl)pyridin-3-yl)-7-azabicyclo[2.2.1]heptane are potential ligands for positron emission tomography imaging of extrathalamic nicotinic acetylcholine receptors.
Gao Y, Horti AG, Kuwabara H, Ravert HT, Hilton J, Holt DP, Kumar A, Alexander M, Endres CJ, Wong DF, Dannals RF. Gao Y, et al. Among authors: ravert ht. J Med Chem. 2007 Aug 9;50(16):3814-24. doi: 10.1021/jm070224t. Epub 2007 Jul 13. J Med Chem. 2007. PMID: 17629263
Discovery of (-)-7-methyl-2-exo-[3'-(6-[18F]fluoropyridin-2-yl)-5'-pyridinyl]-7-azabicyclo[2.2.1]heptane, a radiolabeled antagonist for cerebral nicotinic acetylcholine receptor (alpha4beta2-nAChR) with optimal positron emission tomography imaging properties.
Gao Y, Kuwabara H, Spivak CE, Xiao Y, Kellar K, Ravert HT, Kumar A, Alexander M, Hilton J, Wong DF, Dannals RF, Horti AG. Gao Y, et al. Among authors: ravert ht. J Med Chem. 2008 Aug 14;51(15):4751-64. doi: 10.1021/jm800323d. Epub 2008 Jul 8. J Med Chem. 2008. PMID: 18605717
Synthesis and biological evaluation of novel carbon-11 labeled pyridyl ethers: candidate ligands for in vivo imaging of alpha4beta2 nicotinic acetylcholine receptors (alpha4beta2-nAChRs) in the brain with positron emission tomography.
Gao Y, Ravert HT, Kuwabara H, Xiao Y, Endres CJ, Hilton J, Holt DP, Kumar A, Alexander M, Wong DF, Dannals RF, Horti AG. Gao Y, et al. Among authors: ravert ht. Bioorg Med Chem. 2009 Jul 1;17(13):4367-77. doi: 10.1016/j.bmc.2009.05.021. Epub 2009 May 15. Bioorg Med Chem. 2009. PMID: 19481945 Free PMC article.
Synthesis and in vivo evaluation of (S)-6-(4-fluorophenoxy)-3-((1-[11C]methylpiperidin-3-yl)methyl)-2-o-tolylquinazolin-4(3H)-one, a potential PET tracer for growth hormone secretagogue receptor (GHSR).
Potter R, Horti AG, Ravert HT, Holt DP, Finley P, Scheffel U, Dannals RF, Wahl RL. Potter R, et al. Among authors: ravert ht. Bioorg Med Chem. 2011 Apr 1;19(7):2368-72. doi: 10.1016/j.bmc.2011.02.021. Epub 2011 Feb 16. Bioorg Med Chem. 2011. PMID: 21388815 Free PMC article.
153 results