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Page 1
Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life.
Selle J, Dinger K, Jentgen V, Zanetti D, Will J, Georgomanolis T, Vohlen C, Wilke R, Kojonazarov B, Klymenko O, Mohr J, V Koningsbruggen-Rietschel S, Rhodes CJ, Ulrich A, Hirani D, Nestler T, Odenthal M, Mahabir E, Nayakanti S, Dabral S, Wunderlich T, Priest J, Seeger W, Dötsch J, Pullamsetti SS, Alejandre Alcazar MA. Selle J, et al. Among authors: wilke r. Nat Commun. 2022 Jul 27;13(1):4352. doi: 10.1038/s41467-022-31655-z. Nat Commun. 2022. PMID: 35896539 Free PMC article.
CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia.
Hirani DV, Thielen F, Mansouri S, Danopoulos S, Vohlen C, Haznedar-Karakaya P, Mohr J, Wilke R, Selle J, Grosch T, Mizik I, Odenthal M, Alvira CM, Kuiper-Makris C, Pryhuber GS, Pallasch C, van Koningsbruggen-Rietschel S, Al-Alam D, Seeger W, Savai R, Dötsch J, Alejandre Alcazar MA. Hirani DV, et al. Among authors: wilke r. Inflamm Regen. 2023 Oct 24;43(1):52. doi: 10.1186/s41232-023-00301-6. Inflamm Regen. 2023. PMID: 37876024 Free PMC article.
Perinatal Obesity Sensitizes for Premature Kidney Aging Signaling.
Selle J, Bohl K, Höpker K, Wilke R, Dinger K, Kasper P, Abend B, Schermer B, Müller RU, Kurschat C, Nüsken KD, Nüsken E, Meyer D, Savai Pullamsetti S, Schumacher B, Dötsch J, Alcazar MAA. Selle J, et al. Among authors: wilke r. Int J Mol Sci. 2023 Jan 28;24(3):2508. doi: 10.3390/ijms24032508. Int J Mol Sci. 2023. PMID: 36768831 Free PMC article.
Perinatal Obesity Induces Hepatic Growth Restriction with Increased DNA Damage Response, Senescence, and Dysregulated Igf-1-Akt-Foxo1 Signaling in Male Offspring of Obese Mice.
Kasper P, Selle J, Vohlen C, Wilke R, Kuiper-Makris C, Klymenko O, Bae-Gartz I, Schömig C, Quaas A, Schumacher B, Demir M, Bürger M, Lang S, Martin A, Steffen HM, Goeser T, Dötsch J, Alcazar MAA. Kasper P, et al. Among authors: wilke r. Int J Mol Sci. 2022 May 17;23(10):5609. doi: 10.3390/ijms23105609. Int J Mol Sci. 2022. PMID: 35628414 Free PMC article.