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First progeria monkey model generated using base editor.
Reddy P, Shao Y, Hernandez-Benitez R, Nuñez Delicado E, Izpisua Belmonte JC. Reddy P, et al. Protein Cell. 2020 Dec;11(12):862-865. doi: 10.1007/s13238-020-00765-z. Protein Cell. 2020. PMID: 32729023 Free PMC article. Review. No abstract available.
Selective elimination of mitochondrial mutations in the germline by genome editing.
Reddy P, Ocampo A, Suzuki K, Luo J, Bacman SR, Williams SL, Sugawara A, Okamura D, Tsunekawa Y, Wu J, Lam D, Xiong X, Montserrat N, Esteban CR, Liu GH, Sancho-Martinez I, Manau D, Civico S, Cardellach F, Del Mar O'Callaghan M, Campistol J, Zhao H, Campistol JM, Moraes CT, Izpisua Belmonte JC. Reddy P, et al. Cell. 2015 Apr 23;161(3):459-469. doi: 10.1016/j.cell.2015.03.051. Cell. 2015. PMID: 25910206 Free PMC article.
Establishment of human iPSC-based models for the study and targeting of glioma initiating cells.
Sancho-Martinez I, Nivet E, Xia Y, Hishida T, Aguirre A, Ocampo A, Ma L, Morey R, Krause MN, Zembrzycki A, Ansorge O, Vazquez-Ferrer E, Dubova I, Reddy P, Lam D, Hishida Y, Wu MZ, Esteban CR, O'Leary D, Wahl GM, Verma IM, Laurent LC, Izpisua Belmonte JC. Sancho-Martinez I, et al. Among authors: reddy p. Nat Commun. 2016 Feb 22;7:10743. doi: 10.1038/ncomms10743. Nat Commun. 2016. PMID: 26899176 Free PMC article.
In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming.
Ocampo A, Reddy P, Martinez-Redondo P, Platero-Luengo A, Hatanaka F, Hishida T, Li M, Lam D, Kurita M, Beyret E, Araoka T, Vazquez-Ferrer E, Donoso D, Roman JL, Xu J, Rodriguez Esteban C, Nuñez G, Nuñez Delicado E, Campistol JM, Guillen I, Guillen P, Izpisua Belmonte JC. Ocampo A, et al. Among authors: reddy p. Cell. 2016 Dec 15;167(7):1719-1733.e12. doi: 10.1016/j.cell.2016.11.052. Cell. 2016. PMID: 27984723 Free PMC article.
Interspecies Chimerism with Mammalian Pluripotent Stem Cells.
Wu J, Platero-Luengo A, Sakurai M, Sugawara A, Gil MA, Yamauchi T, Suzuki K, Bogliotti YS, Cuello C, Morales Valencia M, Okumura D, Luo J, Vilariño M, Parrilla I, Soto DA, Martinez CA, Hishida T, Sánchez-Bautista S, Martinez-Martinez ML, Wang H, Nohalez A, Aizawa E, Martinez-Redondo P, Ocampo A, Reddy P, Roca J, Maga EA, Esteban CR, Berggren WT, Nuñez Delicado E, Lajara J, Guillen I, Guillen P, Campistol JM, Martinez EA, Ross PJ, Izpisua Belmonte JC. Wu J, et al. Among authors: reddy p. Cell. 2017 Jan 26;168(3):473-486.e15. doi: 10.1016/j.cell.2016.12.036. Cell. 2017. PMID: 28129541 Free PMC article.
In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation.
Liao HK, Hatanaka F, Araoka T, Reddy P, Wu MZ, Sui Y, Yamauchi T, Sakurai M, O'Keefe DD, Núñez-Delicado E, Guillen P, Campistol JM, Wu CJ, Lu LF, Esteban CR, Izpisua Belmonte JC. Liao HK, et al. Among authors: reddy p. Cell. 2017 Dec 14;171(7):1495-1507.e15. doi: 10.1016/j.cell.2017.10.025. Epub 2017 Dec 7. Cell. 2017. PMID: 29224783 Free PMC article.
In vivo reprogramming of wound-resident cells generates skin epithelial tissue.
Kurita M, Araoka T, Hishida T, O'Keefe DD, Takahashi Y, Sakamoto A, Sakurai M, Suzuki K, Wu J, Yamamoto M, Hernandez-Benitez R, Ocampo A, Reddy P, Shokhirev MN, Magistretti P, Núñez Delicado E, Eto H, Harii K, Izpisua Belmonte JC. Kurita M, et al. Among authors: reddy p. Nature. 2018 Sep;561(7722):243-247. doi: 10.1038/s41586-018-0477-4. Epub 2018 Sep 5. Nature. 2018. PMID: 30185909 Free PMC article.
Mutations in foregut SOX2+ cells induce efficient proliferation via CXCR2 pathway.
Hishida T, Vazquez-Ferrer E, Hishida-Nozaki Y, Sancho-Martinez I, Takahashi Y, Hatanaka F, Wu J, Ocampo A, Reddy P, Wu MZ, Gerken L, Shaw RJ, Rodriguez Esteban C, Benner C, Nakagawa H, Guillen Garcia P, Nuñez Delicado E, Castells A, Campistol JM, Liu GH, Izpisua Belmonte JC. Hishida T, et al. Among authors: reddy p. Protein Cell. 2019 Jul;10(7):485-495. doi: 10.1007/s13238-019-0630-3. Epub 2019 Apr 30. Protein Cell. 2019. PMID: 31041783 Free PMC article.
Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction.
Suzuki K, Yamamoto M, Hernandez-Benitez R, Li Z, Wei C, Soligalla RD, Aizawa E, Hatanaka F, Kurita M, Reddy P, Ocampo A, Hishida T, Sakurai M, Nemeth AN, Nuñez Delicado E, Campistol JM, Magistretti P, Guillen P, Rodriguez Esteban C, Gong J, Yuan Y, Gu Y, Liu GH, López-Otín C, Wu J, Zhang K, Izpisua Belmonte JC. Suzuki K, et al. Among authors: reddy p. Cell Res. 2019 Oct;29(10):804-819. doi: 10.1038/s41422-019-0213-0. Epub 2019 Aug 23. Cell Res. 2019. PMID: 31444470 Free PMC article.
3,591 results