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Design, synthesis and evaluation of monovalent Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP.
González-López M, Welsh K, Finlay D, Ardecky RJ, Ganji SR, Su Y, Yuan H, Teriete P, Mace PD, Riedl SJ, Vuori K, Reed JC, Cosford ND. González-López M, et al. Among authors: reed jc. Bioorg Med Chem Lett. 2011 Jul 15;21(14):4332-6. doi: 10.1016/j.bmcl.2011.05.049. Epub 2011 May 24. Bioorg Med Chem Lett. 2011. PMID: 21680182 Free PMC article.
Design and synthesis of a simplified inhibitor for XIAP-BIR3 domain.
Crisóstomo FR, Feng Y, Zhu X, Welsh K, An J, Reed JC, Huang Z. Crisóstomo FR, et al. Among authors: reed jc. Bioorg Med Chem Lett. 2009 Nov 15;19(22):6413-8. doi: 10.1016/j.bmcl.2009.09.058. Epub 2009 Sep 17. Bioorg Med Chem Lett. 2009. PMID: 19819692 Free PMC article.
Design, synthesis and evaluation of inhibitor of apoptosis protein (IAP) antagonists that are highly selective for the BIR2 domain of XIAP.
Ardecky RJ, Welsh K, Finlay D, Lee PS, González-López M, Ganji SR, Ravanan P, Mace PD, Riedl SJ, Vuori K, Reed JC, Cosford ND. Ardecky RJ, et al. Among authors: reed jc. Bioorg Med Chem Lett. 2013 Jul 15;23(14):4253-7. doi: 10.1016/j.bmcl.2013.04.096. Epub 2013 May 14. Bioorg Med Chem Lett. 2013. PMID: 23743278 Free PMC article.
Binding properties of the C-terminal domain of VIAF.
Bisson WH, Zhang Z, Welsh K, Huang JW, Ryan J, Reed JC, Pellecchia M. Bisson WH, et al. Among authors: reed jc. Chem Biol Drug Des. 2008 Nov;72(5):331-6. doi: 10.1111/j.1747-0285.2008.00719.x. Chem Biol Drug Des. 2008. PMID: 19012568
1,000 results