Reff ME - Search Results

1

Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20.

Reff ME, Carner K, Chambers KS, Chinn PC, Leonard JE, Raab R, Newman RA, Hanna N, Anderson DR. Reff ME, et al. Blood. 1994 Jan 15;83(2):435-45. Blood. 1994. PMID: 7506951 Free article.

2

"Primatization" of recombinant antibodies for immunotherapy of human diseases: a macaque/human chimeric antibody against human CD4.

Newman R, Alberts J, Anderson D, Carner K, Heard C, Norton F, Raab R, Reff M, Shuey S, Hanna N. Newman R, et al. Biotechnology (N Y). 1992 Nov;10(11):1455-60. doi: 10.1038/nbt1192-1455. Biotechnology (N Y). 1992. PMID: 1369023

3

A primatized MAb to human CD4 causes receptor modulation, without marked reduction in CD4+ T cells in chimpanzees: in vitro and in vivo characterization of a MAb (IDEC-CE9.1) to human CD4.

Anderson D, Chambers K, Hanna N, Leonard J, Reff M, Newman R, Baldoni J, Dunleavy D, Reddy M, Sweet R, Truneh A. Anderson D, et al. Clin Immunol Immunopathol. 1997 Jul;84(1):73-84. doi: 10.1006/clin.1997.4363. Clin Immunol Immunopathol. 1997. PMID: 9191886

4

Elimination of Fc receptor-dependent effector functions of a modified IgG4 monoclonal antibody to human CD4.

Reddy MP, Kinney CA, Chaikin MA, Payne A, Fishman-Lobell J, Tsui P, Dal Monte PR, Doyle ML, Brigham-Burke MR, Anderson D, Reff M, Newman R, Hanna N, Sweet RW, Truneh A. Reddy MP, et al. J Immunol. 2000 Feb 15;164(4):1925-33. doi: 10.4049/jimmunol.164.4.1925. J Immunol. 2000. PMID: 10657642

5

Modification of the Fc region of a primatized IgG antibody to human CD4 retains its ability to modulate CD4 receptors but does not deplete CD4(+) T cells in chimpanzees.

Newman R, Hariharan K, Reff M, Anderson DR, Braslawsky G, Santoro D, Hanna N, Bugelski PJ, Brigham-Burke M, Crysler C, Gagnon RC, Dal Monte P, Doyle ML, Hensley PC, Reddy MP, Sweet RW, Truneh A. Newman R, et al. Clin Immunol. 2001 Feb;98(2):164-74. doi: 10.1006/clim.2000.4975. Clin Immunol. 2001. PMID: 11161972

6

Expression of GnTIII in a recombinant anti-CD20 CHO production cell line: Expression of antibodies with altered glycoforms leads to an increase in ADCC through higher affinity for FC gamma RIII.

Davies J, Jiang L, Pan LZ, LaBarre MJ, Anderson D, Reff M. Davies J, et al. Biotechnol Bioeng. 2001 Aug 20;74(4):288-94. Biotechnol Bioeng. 2001. PMID: 11410853

7

In vitro IgE inhibition in B cells by anti-CD23 monoclonal antibodies is functionally dependent on the immunoglobulin Fc domain.

Nakamura T, Kloetzer WS, Brams P, Hariharan K, Chamat S, Cao X, LaBarre MJ, Chinn PC, Morena RA, Shestowsky WS, Li YP, Chen A, Reff ME. Nakamura T, et al. Among authors: reff me. Int J Immunopharmacol. 2000 Feb;22(2):131-41. doi: 10.1016/s0192-0561(99)00068-5. Int J Immunopharmacol. 2000. PMID: 10684997

8

Two neutralizing human anti-RSV antibodies: cloning, expression, and characterization.

Heard C, Brams P, Walsh E, Huynh T, Chamat S, Reff M, Owyang A, Shestowsky W, Newman R. Heard C, et al. Mol Med. 1999 Jan;5(1):35-45. Mol Med. 1999. PMID: 10072446 Free PMC article.

9

Future approaches for treating hematologic disease.

Reff M, Braslawsky G, Hanna N. Reff M, et al. Curr Pharm Biotechnol. 2001 Dec;2(4):369-82. doi: 10.2174/1389201013378626. Curr Pharm Biotechnol. 2001. PMID: 11762418 Review.

10

Measurement of protein interaction bioenergetics: application to structural variants of anti-sCD4 antibody.

Doyle ML, Brigham-Burke M, Blackburn MN, Brooks IS, Smith TM, Newman R, Reff M, Stafford WF 3rd, Sweet RW, Truneh A, Hensley P, O'Shannessy DJ. Doyle ML, et al. Methods Enzymol. 2000;323:207-30. doi: 10.1016/s0076-6879(00)23368-5. Methods Enzymol. 2000. PMID: 10944754

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