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Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration.
Clapes T, Polyzou A, Prater P, Sagar, Morales-Hernández A, Ferrarini MG, Kehrer N, Lefkopoulos S, Bergo V, Hummel B, Obier N, Maticzka D, Bridgeman A, Herman JS, Ilik I, Klaeylé L, Rehwinkel J, McKinney-Freeman S, Backofen R, Akhtar A, Cabezas-Wallscheid N, Sawarkar R, Rebollo R, Grün D, Trompouki E. Clapes T, et al. Among authors: rehwinkel j. Nat Cell Biol. 2021 Jul;23(7):704-717. doi: 10.1038/s41556-021-00707-9. Epub 2021 Jul 12. Nat Cell Biol. 2021. PMID: 34253898 Free PMC article.
SAMHD1-dependent retroviral control and escape in mice.
Rehwinkel J, Maelfait J, Bridgeman A, Rigby R, Hayward B, Liberatore RA, Bieniasz PD, Towers GJ, Moita LF, Crow YJ, Bonthron DT, Reis e Sousa C. Rehwinkel J, et al. EMBO J. 2013 Sep 11;32(18):2454-62. doi: 10.1038/emboj.2013.163. Epub 2013 Jul 19. EMBO J. 2013. PMID: 23872947 Free PMC article.
Sensing of viral and endogenous RNA by ZBP1/DAI induces necroptosis.
Maelfait J, Liverpool L, Bridgeman A, Ragan KB, Upton JW, Rehwinkel J. Maelfait J, et al. Among authors: rehwinkel j. EMBO J. 2017 Sep 1;36(17):2529-2543. doi: 10.15252/embj.201796476. Epub 2017 Jul 17. EMBO J. 2017. PMID: 28716805 Free PMC article.
Mitochondrial double-stranded RNA triggers antiviral signalling in humans.
Dhir A, Dhir S, Borowski LS, Jimenez L, Teitell M, Rötig A, Crow YJ, Rice GI, Duffy D, Tamby C, Nojima T, Munnich A, Schiff M, de Almeida CR, Rehwinkel J, Dziembowski A, Szczesny RJ, Proudfoot NJ. Dhir A, et al. Among authors: rehwinkel j. Nature. 2018 Aug;560(7717):238-242. doi: 10.1038/s41586-018-0363-0. Epub 2018 Jul 25. Nature. 2018. PMID: 30046113 Free PMC article.
Deoxyguanosine is a TLR7 agonist.
Davenne T, Bridgeman A, Rigby RE, Rehwinkel J. Davenne T, et al. Among authors: rehwinkel j. Eur J Immunol. 2020 Jan;50(1):56-62. doi: 10.1002/eji.201948151. Epub 2019 Nov 14. Eur J Immunol. 2020. PMID: 31608988 Free PMC article.
91 results