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Pilot Study of Delayed ICOS/ICOS-L Blockade With αCD40 to Modulate Pathogenic Alloimmunity in a Primate Cardiac Allograft Model.
O'Neill NA, Zhang T, Braileanu G, Cheng X, Hershfeld A, Sun W, Reimann KA, Dahi S, Kubicki N, Hassanein W, Laird C, Cimeno A, Azimzadeh AM, Pierson RN. O'Neill NA, et al. Among authors: reimann ka. Transplant Direct. 2018 Feb 2;4(2):e344. doi: 10.1097/TXD.0000000000000761. eCollection 2018 Feb. Transplant Direct. 2018. PMID: 29464205 Free PMC article.
Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft.
Mohiuddin MM, Singh AK, Corcoran PC, Thomas Iii ML, Clark T, Lewis BG, Hoyt RF, Eckhaus M, Pierson Iii RN, Belli AJ, Wolf E, Klymiuk N, Phelps C, Reimann KA, Ayares D, Horvath KA. Mohiuddin MM, et al. Among authors: reimann ka. Nat Commun. 2016 Apr 5;7:11138. doi: 10.1038/ncomms11138. Nat Commun. 2016. PMID: 27045379 Free PMC article.
Role of anti-CD40 antibody-mediated costimulation blockade on non-Gal antibody production and heterotopic cardiac xenograft survival in a GTKO.hCD46Tg pig-to-baboon model.
Mohiuddin MM, Singh AK, Corcoran PC, Hoyt RF, Thomas ML 3rd, Lewis BG, Eckhaus M, Dabkowski NL, Belli AJ, Reimann KA, Ayares D, Horvath KA. Mohiuddin MM, et al. Among authors: reimann ka. Xenotransplantation. 2014 Jan-Feb;21(1):35-45. doi: 10.1111/xen.12066. Epub 2013 Oct 29. Xenotransplantation. 2014. PMID: 24164510 Free PMC article.
Safety and pharmacodynamics of anti-CD2 monoclonal antibody treatment in cynomolgus macaques - an experimental study.
Berglund E, Alonso-Guallart P, Danton M, Sellberg F, Binder C, Fröbom R, Berglund D, Llore N, Sakai H, Iuga A, Ekanayake-Alper D, Reimann KA, Sachs DH, Sykes M, Griesemer A. Berglund E, et al. Among authors: reimann ka. Transpl Int. 2020 Jan;33(1):98-107. doi: 10.1111/tri.13524. Epub 2019 Nov 15. Transpl Int. 2020. PMID: 31523849 Free PMC article.
Selective Targeting of High-Affinity LFA-1 Does Not Augment Costimulation Blockade in a Nonhuman Primate Renal Transplantation Model.
Samy KP, Anderson DJ, Lo DJ, Mulvihill MS, Song M, Farris AB, Parker BS, MacDonald AL, Lu C, Springer TA, Kachlany SC, Reimann KA, How T, Leopardi FV, Franke KS, Williams KD, Collins BH, Kirk AD. Samy KP, et al. Among authors: reimann ka. Am J Transplant. 2017 May;17(5):1193-1203. doi: 10.1111/ajt.14141. Epub 2017 Jan 27. Am J Transplant. 2017. PMID: 27888551 Free PMC article.
A novel monoclonal antibody to CD40 prolongs islet allograft survival.
Lowe M, Badell IR, Thompson P, Martin B, Leopardi F, Strobert E, Price AA, Abdulkerim HS, Wang R, Iwakoshi NN, Adams AB, Kirk AD, Larsen CP, Reimann KA. Lowe M, et al. Among authors: reimann ka. Am J Transplant. 2012 Aug;12(8):2079-87. doi: 10.1111/j.1600-6143.2012.04054.x. Epub 2012 May 8. Am J Transplant. 2012. PMID: 22845909 Free PMC article.
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