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Page 1
Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling.
Reinhardt P, Glatza M, Hemmer K, Tsytsyura Y, Thiel CS, Höing S, Moritz S, Parga JA, Wagner L, Bruder JM, Wu G, Schmid B, Röpke A, Klingauf J, Schwamborn JC, Gasser T, Schöler HR, Sterneckert J. Reinhardt P, et al. PLoS One. 2013;8(3):e59252. doi: 10.1371/journal.pone.0059252. Epub 2013 Mar 22. PLoS One. 2013. PMID: 23533608 Free PMC article.
Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression.
Reinhardt P, Schmid B, Burbulla LF, Schöndorf DC, Wagner L, Glatza M, Höing S, Hargus G, Heck SA, Dhingra A, Wu G, Müller S, Brockmann K, Kluba T, Maisel M, Krüger R, Berg D, Tsytsyura Y, Thiel CS, Psathaki OE, Klingauf J, Kuhlmann T, Klewin M, Müller H, Gasser T, Schöler HR, Sterneckert J. Reinhardt P, et al. Cell Stem Cell. 2013 Mar 7;12(3):354-67. doi: 10.1016/j.stem.2013.01.008. Cell Stem Cell. 2013. PMID: 23472874 Free article.
Investigating human disease using stem cell models.
Sterneckert JL, Reinhardt P, Schöler HR. Sterneckert JL, et al. Among authors: reinhardt p. Nat Rev Genet. 2014 Sep;15(9):625-39. doi: 10.1038/nrg3764. Epub 2014 Jul 29. Nat Rev Genet. 2014. PMID: 25069490 Review.
Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease.
Marrone L, Bus C, Schöndorf D, Fitzgerald JC, Kübler M, Schmid B, Reinhardt P, Reinhardt L, Deleidi M, Levin T, Meixner A, Klink B, Glatza M, Gloeckner CJ, Gasser T, Sterneckert J. Marrone L, et al. Among authors: reinhardt p, reinhardt l. PLoS One. 2018 Mar 7;13(3):e0192497. doi: 10.1371/journal.pone.0192497. eCollection 2018. PLoS One. 2018. PMID: 29513666 Free PMC article.
Zfp296 is a novel, pluripotent-specific reprogramming factor.
Fischedick G, Klein DC, Wu G, Esch D, Höing S, Han DW, Reinhardt P, Hergarten K, Tapia N, Schöler HR, Sterneckert JL. Fischedick G, et al. Among authors: reinhardt p. PLoS One. 2012;7(4):e34645. doi: 10.1371/journal.pone.0034645. Epub 2012 Apr 2. PLoS One. 2012. PMID: 22485183 Free PMC article.
Discovery of inhibitors of microglial neurotoxicity acting through multiple mechanisms using a stem-cell-based phenotypic assay.
Höing S, Rudhard Y, Reinhardt P, Glatza M, Stehling M, Wu G, Peiker C, Böcker A, Parga JA, Bunk E, Schwamborn JC, Slack M, Sterneckert J, Schöler HR. Höing S, et al. Among authors: reinhardt p. Cell Stem Cell. 2012 Nov 2;11(5):620-32. doi: 10.1016/j.stem.2012.07.005. Epub 2012 Oct 11. Cell Stem Cell. 2012. PMID: 23064101 Free article.
iPS cell derived neuronal cells for drug discovery.
Heilker R, Traub S, Reinhardt P, Schöler HR, Sterneckert J. Heilker R, et al. Among authors: reinhardt p. Trends Pharmacol Sci. 2014 Oct;35(10):510-9. doi: 10.1016/j.tips.2014.07.003. Epub 2014 Aug 3. Trends Pharmacol Sci. 2014. PMID: 25096281 Review.
Origin-dependent neural cell identities in differentiated human iPSCs in vitro and after transplantation into the mouse brain.
Hargus G, Ehrlich M, Araúzo-Bravo MJ, Hemmer K, Hallmann AL, Reinhardt P, Kim KP, Adachi K, Santourlidis S, Ghanjati F, Fauser M, Ossig C, Storch A, Kim JB, Schwamborn JC, Sterneckert J, Schöler HR, Kuhlmann T, Zaehres H. Hargus G, et al. Among authors: reinhardt p. Cell Rep. 2014 Sep 25;8(6):1697-1703. doi: 10.1016/j.celrep.2014.08.014. Epub 2014 Sep 15. Cell Rep. 2014. PMID: 25220454 Free article.
Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein.
Ehrlich M, Hallmann AL, Reinhardt P, Araúzo-Bravo MJ, Korr S, Röpke A, Psathaki OE, Ehling P, Meuth SG, Oblak AL, Murrell JR, Ghetti B, Zaehres H, Schöler HR, Sterneckert J, Kuhlmann T, Hargus G. Ehrlich M, et al. Among authors: reinhardt p. Stem Cell Reports. 2015 Jul 14;5(1):83-96. doi: 10.1016/j.stemcr.2015.06.001. Epub 2015 Jul 2. Stem Cell Reports. 2015. PMID: 26143746 Free PMC article.
Modeling Parkinson's disease in midbrain-like organoids.
Smits LM, Reinhardt L, Reinhardt P, Glatza M, Monzel AS, Stanslowsky N, Rosato-Siri MD, Zanon A, Antony PM, Bellmann J, Nicklas SM, Hemmer K, Qing X, Berger E, Kalmbach N, Ehrlich M, Bolognin S, Hicks AA, Wegner F, Sterneckert JL, Schwamborn JC. Smits LM, et al. Among authors: reinhardt p, reinhardt l. NPJ Parkinsons Dis. 2019 Apr 5;5:5. doi: 10.1038/s41531-019-0078-4. eCollection 2019. NPJ Parkinsons Dis. 2019. PMID: 30963107 Free PMC article.
131 results