Renga B - Search Results

1

Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands.

Festa C, Renga B, D'Amore C, Sepe V, Finamore C, De Marino S, Carino A, Cipriani S, Monti MC, Zampella A, Fiorucci S. Festa C, et al. Among authors: renga b. J Med Chem. 2014 Oct 23;57(20):8477-95. doi: 10.1021/jm501273r. Epub 2014 Oct 9. J Med Chem. 2014. PMID: 25247751

2

Discovery of sulfated sterols from marine invertebrates as a new class of marine natural antagonists of farnesoid-X-receptor.

Sepe V, Bifulco G, Renga B, D'Amore C, Fiorucci S, Zampella A. Sepe V, et al. Among authors: renga b. J Med Chem. 2011 Mar 10;54(5):1314-20. doi: 10.1021/jm101336m. Epub 2011 Feb 10. J Med Chem. 2011. PMID: 21309576

3

Theonellasterols and conicasterols from Theonella swinhoei. Novel marine natural ligands for human nuclear receptors.

De Marino S, Ummarino R, D'Auria MV, Chini MG, Bifulco G, Renga B, D'Amore C, Fiorucci S, Debitus C, Zampella A. De Marino S, et al. Among authors: renga b. J Med Chem. 2011 Apr 28;54(8):3065-75. doi: 10.1021/jm200169t. Epub 2011 Apr 5. J Med Chem. 2011. PMID: 21428459

4

Total synthesis and pharmacological characterization of solomonsterol A, a potent marine pregnane-X-receptor agonist endowed with anti-inflammatory activity.

Sepe V, Ummarino R, D'Auria MV, Mencarelli A, D'Amore C, Renga B, Zampella A, Fiorucci S. Sepe V, et al. Among authors: renga b. J Med Chem. 2011 Jul 14;54(13):4590-9. doi: 10.1021/jm200241s. Epub 2011 Jun 3. J Med Chem. 2011. PMID: 21599020

5

Conicasterol E, a small heterodimer partner sparing farnesoid X receptor modulator endowed with a pregnane X receptor agonistic activity, from the marine sponge Theonella swinhoei.

Sepe V, Ummarino R, D'Auria MV, Chini MG, Bifulco G, Renga B, D'Amore C, Debitus C, Fiorucci S, Zampella A. Sepe V, et al. Among authors: renga b. J Med Chem. 2012 Jan 12;55(1):84-93. doi: 10.1021/jm201004p. Epub 2011 Dec 14. J Med Chem. 2012. PMID: 22126372

6

Plakilactones from the marine sponge Plakinastrella mamillaris. Discovery of a new class of marine ligands of peroxisome proliferator-activated receptor γ.

Festa C, Lauro G, De Marino S, D'Auria MV, Monti MC, Casapullo A, D'Amore C, Renga B, Mencarelli A, Petek S, Bifulco G, Fiorucci S, Zampella A. Festa C, et al. Among authors: renga b. J Med Chem. 2012 Oct 11;55(19):8303-17. doi: 10.1021/jm300911g. Epub 2012 Sep 19. J Med Chem. 2012. PMID: 22934537

7

Binding mechanism of the farnesoid X receptor marine antagonist suvanine reveals a strategy to forestall drug modulation on nuclear receptors. Design, synthesis, and biological evaluation of novel ligands.

Di Leva FS, Festa C, D'Amore C, De Marino S, Renga B, D'Auria MV, Novellino E, Limongelli V, Zampella A, Fiorucci S. Di Leva FS, et al. Among authors: renga b. J Med Chem. 2013 Jun 13;56(11):4701-17. doi: 10.1021/jm400419e. Epub 2013 May 24. J Med Chem. 2013. PMID: 23656455

8

Isoswinholide B and swinholide K, potently cytotoxic dimeric macrolides from Theonella swinhoei.

Sinisi A, Calcinai B, Cerrano C, Dien HA, Zampella A, D'Amore C, Renga B, Fiorucci S, Taglialatela-Scafati O. Sinisi A, et al. Among authors: renga b. Bioorg Med Chem. 2013 Sep 1;21(17):5332-8. doi: 10.1016/j.bmc.2013.06.015. Epub 2013 Jun 15. Bioorg Med Chem. 2013. PMID: 23830699

9

Design, synthesis, and biological evaluation of potent dual agonists of nuclear and membrane bile acid receptors.

D'Amore C, Di Leva FS, Sepe V, Renga B, Del Gaudio C, D'Auria MV, Zampella A, Fiorucci S, Limongelli V. D'Amore C, et al. Among authors: renga b. J Med Chem. 2014 Feb 13;57(3):937-54. doi: 10.1021/jm401873d. Epub 2014 Jan 17. J Med Chem. 2014. PMID: 24387325

10

Insights on pregnane-X-receptor modulation. Natural and semisynthetic steroids from Theonella marine sponges.

Sepe V, D'Amore C, Ummarino R, Renga B, D'Auria MV, Novellino E, Sinisi A, Taglialatela-Scafati O, Nakao Y, Limongelli V, Zampella A, Fiorucci S. Sepe V, et al. Among authors: renga b. Eur J Med Chem. 2014 Feb 12;73:126-34. doi: 10.1016/j.ejmech.2013.12.005. Epub 2013 Dec 15. Eur J Med Chem. 2014. PMID: 24388834

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