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Year Number of Results
2016 3
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2019 8
2020 5
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2023 6
2024 1

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PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism.
Ren AA, Snellings DA, Su YS, Hong CC, Castro M, Tang AT, Detter MR, Hobson N, Girard R, Romanos S, Lightle R, Moore T, Shenkar R, Benavides C, Beaman MM, Müller-Fielitz H, Chen M, Mericko P, Yang J, Sung DC, Lawton MT, Ruppert JM, Schwaninger M, Körbelin J, Potente M, Awad IA, Marchuk DA, Kahn ML. Ren AA, et al. Among authors: lightle r. Nature. 2021 Jun;594(7862):271-276. doi: 10.1038/s41586-021-03562-8. Epub 2021 Apr 28. Nature. 2021. PMID: 33910229 Free PMC article.
Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation.
Lopez-Ramirez MA, Lai CC, Soliman SI, Hale P, Pham A, Estrada EJ, McCurdy S, Girard R, Verma R, Moore T, Lightle R, Hobson N, Shenkar R, Poulsen O, Haddad GG, Daneman R, Gongol B, Sun H, Lagarrigue F, Awad IA, Ginsberg MH. Lopez-Ramirez MA, et al. Among authors: lightle r. J Clin Invest. 2021 Jul 1;131(13):e139570. doi: 10.1172/JCI139570. J Clin Invest. 2021. PMID: 34043589 Free PMC article.
Endothelial TLR4 and the microbiome drive cerebral cavernous malformations.
Tang AT, Choi JP, Kotzin JJ, Yang Y, Hong CC, Hobson N, Girard R, Zeineddine HA, Lightle R, Moore T, Cao Y, Shenkar R, Chen M, Mericko P, Yang J, Li L, Tanes C, Kobuley D, Võsa U, Whitehead KJ, Li DY, Franke L, Hart B, Schwaninger M, Henao-Mejia J, Morrison L, Kim H, Awad IA, Zheng X, Kahn ML. Tang AT, et al. Among authors: lightle r. Nature. 2017 May 18;545(7654):305-310. doi: 10.1038/nature22075. Epub 2017 May 10. Nature. 2017. PMID: 28489816 Free PMC article.
Transcriptomic signatures of individual cell types in cerebral cavernous malformation.
Li Y, Girard R, Srinath A, Cruz DV, Ciszewski C, Chen C, Lightle R, Romanos S, Sone JY, Moore T, DeBiasse D, Stadnik A, Lee JJ, Shenkar R, Koskimäki J, Lopez-Ramirez MA, Marchuk DA, Ginsberg MH, Kahn ML, Shi C, Awad IA. Li Y, et al. Among authors: lightle r. Cell Commun Signal. 2024 Jan 9;22(1):23. doi: 10.1186/s12964-023-01301-2. Cell Commun Signal. 2024. PMID: 38195510 Free PMC article.
Plasma metabolites with mechanistic and clinical links to the neurovascular disease cavernous angioma.
Srinath A, Xie B, Li Y, Sone JY, Romanos S, Chen C, Sharma A, Polster S, Dorrestein PC, Weldon KC, DeBiasse D, Moore T, Lightle R, Koskimäki J, Zhang D, Stadnik A, Piedad K, Hagan M, Shkoukani A, Carrión-Penagos J, Bi D, Shen L, Shenkar R, Ji Y, Sidebottom A, Pamer E, Gilbert JA, Kahn ML, D'Souza M, Sulakhe D, Awad IA, Girard R. Srinath A, et al. Among authors: lightle r. Commun Med (Lond). 2023 Mar 3;3(1):35. doi: 10.1038/s43856-023-00265-1. Commun Med (Lond). 2023. PMID: 36869161 Free PMC article.
35 results