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ECM1 secreted by HER2-overexpressing breast cancer cells promotes formation of a vascular niche accelerating cancer cell migration and invasion.
Steinhaeuser SS, Morera E, Budkova Z, Schepsky A, Wang Q, Rolfsson O, Riedel A, Krueger A, Hilmarsdottir B, Maelandsmo GM, Valdimarsdottir B, Sigurdardottir AK, Agnarsson BA, Jonasson JG, Ingthorsson S, Traustadottir GA, Oskarsson T, Gudjonsson T. Steinhaeuser SS, et al. Among authors: riedel a. Lab Invest. 2020 Jul;100(7):928-944. doi: 10.1038/s41374-020-0415-6. Epub 2020 Mar 18. Lab Invest. 2020. PMID: 32203150 Free article.
Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth.
Davidson S, Efremova M, Riedel A, Mahata B, Pramanik J, Huuhtanen J, Kar G, Vento-Tormo R, Hagai T, Chen X, Haniffa MA, Shields JD, Teichmann SA. Davidson S, et al. Among authors: riedel a. Cell Rep. 2020 May 19;31(7):107628. doi: 10.1016/j.celrep.2020.107628. Cell Rep. 2020. PMID: 32433953 Free PMC article.
Tumors induce de novo steroid biosynthesis in T cells to evade immunity.
Mahata B, Pramanik J, van der Weyden L, Polanski K, Kar G, Riedel A, Chen X, Fonseca NA, Kundu K, Campos LS, Ryder E, Duddy G, Walczak I, Okkenhaug K, Adams DJ, Shields JD, Teichmann SA. Mahata B, et al. Among authors: riedel a. Nat Commun. 2020 Jul 17;11(1):3588. doi: 10.1038/s41467-020-17339-6. Nat Commun. 2020. PMID: 32680985 Free PMC article.
ILC2-driven innate immune checkpoint mechanism antagonizes NK cell antimetastatic function in the lung.
Schuijs MJ, Png S, Richard AC, Tsyben A, Hamm G, Stockis J, Garcia C, Pinaud S, Nicholls A, Ros XR, Su J, Eldridge MD, Riedel A, Serrao EM, Rodewald HR, Mack M, Shields JD, Cohen ES, McKenzie ANJ, Goodwin RJA, Brindle KM, Marioni JC, Halim TYF. Schuijs MJ, et al. Among authors: riedel a. Nat Immunol. 2020 Sep;21(9):998-1009. doi: 10.1038/s41590-020-0745-y. Epub 2020 Aug 3. Nat Immunol. 2020. PMID: 32747815 Free PMC article.
Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs.
Hongu T, Pein M, Insua-Rodríguez J, Gutjahr E, Mattavelli G, Meier J, Decker K, Descot A, Bozza M, Harbottle R, Trumpp A, Sinn HP, Riedel A, Oskarsson T. Hongu T, et al. Among authors: riedel a. Nat Cancer. 2022 Apr;3(4):486-504. doi: 10.1038/s43018-022-00353-6. Epub 2022 Apr 25. Nat Cancer. 2022. PMID: 35469015 Free PMC article.
Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation.
Miragaia RJ, Gomes T, Chomka A, Jardine L, Riedel A, Hegazy AN, Whibley N, Tucci A, Chen X, Lindeman I, Emerton G, Krausgruber T, Shields J, Haniffa M, Powrie F, Teichmann SA. Miragaia RJ, et al. Among authors: riedel a. Immunity. 2019 Feb 19;50(2):493-504.e7. doi: 10.1016/j.immuni.2019.01.001. Epub 2019 Feb 5. Immunity. 2019. PMID: 30737144 Free PMC article.
270 results