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The antifungal antibiotic, clotrimazole, inhibits chloride secretion by human intestinal T84 cells via blockade of distinct basolateral K+ conductances. Demonstration of efficacy in intact rabbit colon and in an in vivo mouse model of cholera.
Rufo PA, Merlin D, Riegler M, Ferguson-Maltzman MH, Dickinson BL, Brugnara C, Alper SL, Lencer WI. Rufo PA, et al. Among authors: riegler m. J Clin Invest. 1997 Dec 15;100(12):3111-20. doi: 10.1172/JCI119866. J Clin Invest. 1997. PMID: 9399958 Free PMC article.
Bacteroides fragilis toxin 2 damages human colonic mucosa in vitro.
Riegler M, Lotz M, Sears C, Pothoulakis C, Castagliuolo I, Wang CC, Sedivy R, Sogukoglu T, Cosentini E, Bischof G, Feil W, Teleky B, Hamilton G, LaMont JT, Wenzl E. Riegler M, et al. Gut. 1999 Apr;44(4):504-10. doi: 10.1136/gut.44.4.504. Gut. 1999. PMID: 10075957 Free PMC article.
Effects of substance P on human colonic mucosa in vitro.
Riegler M, Castagliuolo I, So PT, Lotz M, Wang C, Wlk M, Sogukoglu T, Cosentini E, Bischof G, Hamilton G, Teleky B, Wenzl E, Matthews JB, Pothoulakis C. Riegler M, et al. Am J Physiol. 1999 Jun;276(6):G1473-83. doi: 10.1152/ajpgi.1999.276.6.G1473. Am J Physiol. 1999. PMID: 10362651
252 results