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Page 1
BacPROTACs mediate targeted protein degradation in bacteria.
Morreale FE, Kleine S, Leodolter J, Junker S, Hoi DM, Ovchinnikov S, Okun A, Kley J, Kurzbauer R, Junk L, Guha S, Podlesainski D, Kazmaier U, Boehmelt G, Weinstabl H, Rumpel K, Schmiedel VM, Hartl M, Haselbach D, Meinhart A, Kaiser M, Clausen T. Morreale FE, et al. Among authors: kurzbauer r. Cell. 2022 Jun 23;185(13):2338-2353.e18. doi: 10.1016/j.cell.2022.05.009. Epub 2022 Jun 3. Cell. 2022. PMID: 35662409 Free PMC article.
Structure of McsB, a protein kinase for regulated arginine phosphorylation.
Suskiewicz MJ, Hajdusits B, Beveridge R, Heuck A, Vu LD, Kurzbauer R, Hauer K, Thoeny V, Rumpel K, Mechtler K, Meinhart A, Clausen T. Suskiewicz MJ, et al. Among authors: kurzbauer r. Nat Chem Biol. 2019 May;15(5):510-518. doi: 10.1038/s41589-019-0265-y. Epub 2019 Apr 8. Nat Chem Biol. 2019. PMID: 30962626 Free PMC article.
HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain.
Grabarczyk DB, Petrova OA, Deszcz L, Kurzbauer R, Murphy P, Ahel J, Vogel A, Gogova R, Faas V, Kordic D, Schleiffer A, Meinhart A, Imre R, Lehner A, Neuhold J, Bader G, Stolt-Bergner P, Böttcher J, Wolkerstorfer B, Fischer G, Grishkovskaya I, Haselbach D, Kessler D, Clausen T. Grabarczyk DB, et al. Among authors: kurzbauer r. Nat Chem Biol. 2021 Oct;17(10):1084-1092. doi: 10.1038/s41589-021-00831-5. Epub 2021 Jul 22. Nat Chem Biol. 2021. PMID: 34294896 Free PMC article.
Structural basis for the disaggregase activity and regulation of Hsp104.
Heuck A, Schitter-Sollner S, Suskiewicz MJ, Kurzbauer R, Kley J, Schleiffer A, Rombaut P, Herzog F, Clausen T. Heuck A, et al. Among authors: kurzbauer r. Elife. 2016 Nov 30;5:e21516. doi: 10.7554/eLife.21516. Elife. 2016. PMID: 27901467 Free PMC article.
19 results